Next generation imaging to bridge the knowledge gap in nanomedicine delivery

下一代成像弥合纳米医学输送方面的知识差距

• 批准号: nhmrc : GNT1148582
• 负责人: A/Pr Kristofer Thurecht
• 金额: $ 47.67万
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/generation-imaging-bridge-nanomedicine-delivery/1348882
• 关键词: Next; generation; imaging; bridge; knowledge

Nanomedicines are generally touted as the next generation in therapeutics. However, despite some landmark successes, their translation into clinical use is limited. This is mainly a result of poor understanding of how they behave under physiological conditions. To address this issue and improve translation, this fellowship aims to develop predictive models of how nanomedicines interact with biological systems, then validate the nanomedicines in dog models of cancer that mimic the human disease.

纳米医学通常被吹捧为治疗学的下一代。然而，尽管取得了一些具有里程碑意义的成功，但其转化为临床应用是有限的。这主要是由于对它们在生理条件下的行为缺乏了解。为了解决这个问题并改善翻译，该奖学金旨在开发纳米药物如何与生物系统相互作用的预测模型，然后在模拟人类疾病的狗癌症模型中验证纳米药物。