Genital Infection Symptoms Among Syrian Refugee Women in Lebanon: A Mixed-Methods Study to Adapt, Pilot Test, and Preliminarily Evaluate an Evidence-Based Intervention

黎巴嫩叙利亚难民妇女的生殖器感染症状：一项混合方法研究，以适应、试点测试和初步评估循证干预措施

• 批准号: 10805723
• 负责人: Sasha Fahme
• 金额: $ 18.52万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-16 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10805723
• 关键词: Acute; Address; American; Appointment; Area; Bacterial Vaginosis; Caring; Cervical Cancer Screening; Chlamydia trachomatis; Client; Clinic; Clinical; Cluster randomized trial; Cohort Studies; Communities; Consult; Continuity of Patient Care; Cross-Sectional Studies; Data; Diabetes Mellitus; Diagnostic tests; Education; Educational workshop; Environment; Epidemiology; Ethics; Etiology; Evidence based intervention; Feasibility Studies; Female; Fogarty International Center; Fostering; Fright; Gender; Gender Identity; Genital; Genitalia; Goals; Grant; Guidelines; HIV; Health; Health Services Accessibility; Healthcare; Human immunodeficiency virus test; Hybrids; Hygiene; Infection; Infection prevention; Infertility; Internal Medicine; International; Internist; Intervention; Interview; Leadership; Learning; Lebanon; Master of Science; Measures; Medical; Medicine; Mentors; Mentorship; Methodology; Methods; Modeling; Neisseria gonorrhoeae; New York; Outcome; Outcome Assessment; Participant; Pathogen detection; Peru; Physicians; Population; Positive Test Result; Prevention; Provider; Public Health; Recurrence; Refugees; Reproductive Health; Research; Research Methodology; Research Personnel; Research Project Grants; Resources; Retreatment; Risk; Risk Factors; Rural; Sampling; Scientist; Self Efficacy; Service provision; Sexual Health; Sexually Transmitted Diseases; Symptoms; Testing; Training; Translating; Trichomonas vaginalis; Underserved Population; Universities; Vulvovaginal Candidiasis; Woman; Women' s Health; Writing; barrier to care; career; career development; chronic pain; data integration; dissemination science; effectiveness study; evidence base; experience; genital infection; health disparity; health science research; implementation outcomes; implementation science; implementation strategy; implementation/effectiveness; improved; intervention refinement; low health literacy; maltreatment; medical schools; novel; obstetrical complication; peer; pilot test; prevent; recruit; recurrent infection; response; rural area; rural residence; rural setting; satisfaction; sex; sexual health intervention; sexual risk behavior; skill acquisition; skills; symposium; systematic review; tool; transmission process; virtual

PROJECT SUMMARY/ABSTRACT Candidate. Dr. Sasha Fahme is an Internal Medicine-trained physician-scientist who has spent the past four years conducting refugee health research in Lebanon. She has first-hand experience treating sexually transmitted infections (STIs) and conducting sexual and reproductive health (SRH) studies of Syrian refugee women. She has trained a Lebanese research team and Syrian peer educators to conduct SRH research and has established capacity for STI testing. Her preliminary data suggest that Syrian refugee women are eager to learn about SRH from peers and to engage in longitudinal SRH care, with 89% 1-year retention. She seeks to adapt and pilot-test an evidence-based intervention (EBI) to address barriers to SRH care in this population. Career Goals. Dr. Fahme's goals are: 1. To gain expertise in mixed-methods health sciences research. 2. To strengthen experience in the conduct of humanitarian health research. 3. To foster implementation science skills to develop and evaluate evidence-based interventions. 4. To develop skills in dissemination to translate research findings into practice. 5. To build leadership skills and successfully compete for R01 research grants. Career Development. Dr. Fahme will achieve her goals through workshops, virtual courses, and one-on-one mentored training from Dr. Fitzgerald (career mentorship, humanitarian health, STI epidemiology) Dr. DeJong (mixed-methods, humanitarian health), Dr. Downs (implementation science), and Dr. Abu-Raddad (STI epidemiology, dissemination). She will disseminate contextualized STI guidelines based on her findings, and present her research at international conferences. She will participate in grant-writing workshops and submit an R01 proposal of a hybrid type I cluster-randomized trial to improve Syrian refugee women's SRH in Year 5. Environment. The proposed research and training will take place at Weill Cornell Medical College (New York, USA) and at the American University of Beirut (Beirut, Lebanon), a global leader in refugee health research. Research. Syrian refugee women in Lebanon are among the world's largest and most vulnerable displaced populations, with a high burden of genital infection symptoms. The etiologies of these symptoms are not known and access to treatment is limited by numerous barriers that are most acute among rural women. Dr. Fahme will recruit 204 symptomatic, rural Syrian refugee women to participate in a longitudinal mixed-methods study. She hypothesizes that >30% will experience recurrent genital infections, and that guidelines fail to address drivers of recurrence, which she will explore through in-depth interviews. She will use these data, the ADAPT- ITT model, and the Implementation Outcomes Framework to adapt and evaluate an EBI to address genital infection symptoms in a single-group pilot feasibility study among 30 Syrian refugee women.

项目总结/摘要 候选人Sasha Fahme博士是一位内科学专业的医生兼科学家， 在黎巴嫩进行难民健康研究。她有第一手的经验 传播感染，并对叙利亚难民进行性健康和生殖健康研究 妇女她培训了一个黎巴嫩研究小组和叙利亚同伴教育者进行性健康和生殖健康研究， 建立了性传播感染检测能力。她的初步数据表明，叙利亚难民妇女渴望 从同龄人那里了解性健康和生殖健康，并参与纵向性健康和生殖健康护理，一年保留率为89%。她试图 调整和试点测试循证干预措施，以解决这一人群在性健康和生殖健康护理方面的障碍。 职业目标。Fahme博士的目标是： 1.获得混合方法健康科学研究的专业知识。 2.加强开展人道主义卫生研究的经验。 3.培养实施科学技能，以制定和评价循证干预措施。 4.发展传播技能，将研究成果转化为实践。 5.培养领导能力，成功竞争R 01研究赠款。 职业发展。Fahme博士将通过研讨会、虚拟课程和一对一的方式来实现她的目标 Fitzgerald博士的指导培训（职业指导、人道主义健康、性传播感染流行病学） （混合方法，人道主义卫生）、唐斯博士（实施科学）和Abu-Raddad博士（科学、技术和创新 流行病学、传播）。她将根据自己的调查结果，传播符合具体情况的科学、技术和创新指南， 在国际会议上展示她的研究成果。她将参加赠款写作研讨会，并提交 一项R 01建议，即在第5年进行一项混合I型群集随机试验，以改善叙利亚难民妇女的性健康和生殖健康。 环境拟议的研究和培训将在威尔康奈尔医学院（纽约， 美国）和贝鲁特美国大学（贝鲁特，黎巴嫩），难民健康研究的全球领导者。 Research.黎巴嫩的叙利亚难民妇女是世界上最大和最脆弱的流离失所者之一 这是一个非常严重的问题，因为这是一个生殖器感染症状负担很高的群体。这些症状的病因尚不清楚 获得治疗的机会受到许多障碍的限制，这些障碍在农村妇女中最为严重。法默博士 将招募204名有症状的叙利亚农村难民妇女参加纵向混合方法研究。 她假设>30%的人会经历复发性生殖器感染，并且指南未能解决 复发的驱动因素，她将通过深入访谈进行探讨。她将使用这些数据，适应- ITT模型和实施成果框架，以适应和评估EBI，以解决生殖器问题 在30名叙利亚难民妇女中进行的一项单组试点可行性研究中，