Regulating axon guidance through local translation at adhesions

项目总结 这份促进健康相关研究多样性的研究附录(PA-21-071)旨在 支持乔丹·海登在我的实验室进行博士前培训。这项建议是一项 对我目前资助的NIH R01奖(NS125146)的补充。在提案中，我们提供了一个 原(家长)R01小结，一份求职者的研究计划，一份职业发展计划 为候选人制定计划，以及PI指导候选人的资格。海登女士 在鲍尔州立大学获得生物学理学学士学位。在此期间 本科时，她在阿什利·卡林斯基博士的神经科学实验室工作，检查 神经损伤后神经炎症的分子机制。作为一种 在大学期间，海登女士出版了一本合著的出版物。海登女士的长期 职业规划是成为学术界的一名独立教员，专注于研究 在神经科学方面。本增刊将为Heden女士提供丰富的研究经验 在分子和细胞神经生物学方面，重点研究局部翻译的潜在机制 在轴突引导过程中。此外，这份增刊将为海登女士提供有重点的 职业发展培训。总体而言，本补编将提供提交所需的培训 在博士课程第三年开始的时候，她申请了一份很好的F31，并帮助她 实现她成为学术界神经科学教授的目标。

PROJECT SUMMARY This Research Supplement to Promote Diversity in Health-Related Research (PA-21-071) is to support Jordan Headen to pursue predoctoral training in my laboratory. This proposal is a supplement to my currently funded NIH R01 award (NS125146). In the proposal, we provide a summary of the original (parent) R01, a research plan for the candidate, a career development plan for the candidate, and the PI’s qualifications to mentor the candidate. Ms. Headen completed her Bachelor of Science degree in Biology at Ball State University. During her undergraduate, she worked in the Neuroscience laboratory of Dr. Ashley Kalinski, examining molecular mechanisms contributing to neuroinflammation after nerve injury. As an undergraduate, Ms. Headen published one co-authored publication. Ms. Headen’s long-term career plans are to become an independent faculty member in academia with a research focus on neuroscience. This supplement will provide Ms. Headen with extensive research experience in molecular and cellular neurobiology, focusing on mechanisms underlying local translation during axon guidance. Furthermore, this supplement will provide Ms. Headen with focused career development training. Overall, this supplement will provide the training needed to submit a strong F31 application at the beginning of her third year in the Ph.D. program and help her achieve her goal of becoming a neuroscience professor in academia.