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中文摘要
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行政核心--摘要 UTMB-诺华大流行防备联盟(UNAPP)结合了UTMB在病毒学方面的卓越表现 &BSL4/3设施与诺华公司在药物发现和开发方面的权力,以提供大流行抗病毒药物。这个 管理核心提供充分实现影响所需的领导和方案协调 这一独特的学术和行业合作伙伴关系,并满足抗病毒药物发现中心的目标 流行病的病原体令人担忧。我们将通过以下四个目标实现这一目标:一、落实 综合组织治理和方案结构,将促进团队科学方法 用于预防冠状病毒、黄病毒和亨尼帕病毒大流行的抗病毒药物的发现; 在科学、运营、金融、知识产权保护和 通过凝聚力和协作治理进行沟通;三.实施发展性研究 项目计划,将扩大中心的研究范围和范围,同时鼓励外部 研究人员在抗病毒药物发现方面开发新技术和创新研究思路;以及iv. 实施指导项目计划,旨在增加合格的早期职业研究人员的可用性 通过提供职业发展和指导研究来促进他们的抗病毒发现研究 职业发展。
英文摘要
ADMINISTRATIVE CORE - ABSTRACT The “UTMB-Novartis Alliance for Pandemic Preparedness (UNAPP)” combines UTMB’s excellence in virology & BSL4/3 facility with Novartis’ power in drug discovery & development to deliver pandemic antivirals. The Administrative Core provides the leadership and programmatic coordination required to fully realize the impact of this unique academic-industry partnership and meet the goals of the Antiviral Drug Discovery Centers for Pathogens of Pandemics Concern. We will accomplish this through the following four aims: i. implement an integrated organizational governance and programmatic structure that will promote a team science approach to antiviral drug discovery for pandemic prevention against Coronaviruses, Flaviviruses, and Henipaviruses; ii. provide integrated decision making in scientific, operational, financial, intellectual property protection and communication through cohesive and collaborative governance; iii. implement a Developmental Research Project program that will expand the center's scope and range of research while encouraging outside investigators to develop novel technology and innovative research ideas in antiviral drug discovery; and iv. implement a Mentored Project program designed to increase the availability of qualified early career researchers in antiviral discovery research by providing career development and mentored research to further their professional advancement.
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Administrative Core
Discovery of novel broad-spectrum coronavirus inhibitors
Discovery of novel broad-spectrum coronavirus inhibitors
Identifying host and viral correlates for coronavirus pathogenesis
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