AHOMKA: A Culturally-adapted mHealth Platform for Management of Hypertension in an Urban and Rural Region of Ghana

项目摘要 包括癌症、心血管疾病、糖尿病在内的非传染性疾病已成为全球最严重的疾病， 低收入和中等收入国家（LMIC）面临的最大健康威胁。在加纳，高血压被认为是 重大公共卫生挑战。移动的电话在加纳的普及和移动的 通信使我们能够向目标人群提供移动健康干预措施。不过有 对基于移动的卫生技术的高血压干预措施的有效性的认识存在重大差距 管理在SSA。拟议的AHOMKA移动健康平台是一项基于证据的干预措施， 在加纳的一个城市和农村地区进行高血压的管理。AHOMKA改编自 Empower HealthTM系统是由Medtronic开发的一种专有软件应用程序，用于直接从患者到 提供者通过移动的应用程序进行通信，以及通过文本消息进行高血压管理。这个美国- 加纳合作R21/R33研究项目将重点关注Empower HealthTM系统的适应性， 通过与利益攸关方的多层次接触，在加纳的城市和农村地区的地方背景下开展工作。我们有 组建了一个由研究人员和医疗器械专业人员组成的跨国、多学科团队， 移动的技术开发、高血压、心脏病学、人口研究和公共卫生方面的专业知识 在加纳的多个机构（加纳大学、健康与联合科学大学、美敦力 实验室加纳）和美国（贝丝以色列女执事医疗中心，塔夫茨大学）。建议的可行性 研究将在大阿克拉地区和沃尔特地区的两个大型心血管诊所进行， 加纳.第一阶段的目标是（1）实施以用户为中心的迭代设计方法，以适应移动健康 根据利益相关者的反馈建立平台，以及（2）进行为期6个月的可用性和可行性研究， 患者队列。第二阶段旨在进行为期12个月的可行性研究，以评估血液中的变化 在加纳的两个地区的患者队列中的压力。为了加速移动的健康研究， 在加纳，我们建议建立AHOMKA研究和教育网络，作为战略能力的一部分。 建筑平面图

PROJECT SUMMARY Non-communicable diseases (NCDs), including cancer, cardiovascular disease, diabetes, have become the greatest health threat for low and middle-income countries (LMIC). In Ghana, hypertension is recognized as a major public health challenge. The ubiquity of mobile phones in Ghana and the popularity of mobile communications make it possible to deliver mHealth interventions to our target population. However, there is crucial gap in knowledge of the effectiveness of mobile health technology-based interventions for hypertension management in SSA. The proposed AHOMKA mHealth platform is an evidence-based intervention to assist with management of hypertension in an urban and rural region of Ghana. AHOMKA is adapted from the Empower HealthTM system, a proprietary software application developed by Medtronic for direct patient-to- provider communication via a mobile application and text messaging for hypertension management. This US- Ghana collaborative R21/R33 research project will focus on adaptation of the Empower HealthTM system into the local context in an urban and rural region of Ghana by multi-level engagement with stakeholders. We have assembled a multi-national, multi-disciplinary team of researchers and medical device professionals with expertise in mobile technology development, hypertension, cardiology, population studies, and public health across multiple institutions in Ghana (University of Ghana, University of Health and Allied Sciences, Medtronic Labs Ghana) and the USA (Beth Israel Deaconess Medical Center, Tufts University). The proposed feasibility studies will be conducted at two large cardiovascular clinics in the Greater Accra region and the Volta region in Ghana. Phase One aims to (1) implement a user-centered, iterative design approach to adapt the mHealth platform based on feedback from stakeholders, and (2) conduct a 6-month usability and feasibility study with a cohort of patients. Phase Two aims to conduct a 12-month feasibility study to assess change in blood pressure among a cohort of patients in two regions of Ghana. In order to accelerate mobile health research in Ghana, we propose to form the AHOMKA Research and Education Network as part of the strategic capacity building plan.