Advanced Development of a Vaccine for Acute Flaccid Myelitis Associated with Enterovirus D68
Advanced Development of a Vaccine for Acute Flaccid Myelitis Associated with Enterovirus D68
批准号:
10881869
负责人:
DINJA OOSTERHOFF
金额:
$108.59万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
未结题
起止时间:
2020-09-01 至 2025-01-31
关键词:
Advanced DevelopmentAnimal ModelCategoriesChildhoodClinicalCommunicable DiseasesContractsDevelopmentDisease OutbreaksEmerging Communicable DiseasesEnterovirus 68FormulationIndividualNational Institute of Allergy and Infectious DiseasePediatric ResearchPopulationSafetyToxicologyVaccinesacute flaccid myelitisefficacy evaluationefficacy testingimmunogenicitymanufacturepriority pathogenresponsestability testingvaccine development
中文摘要
支持候选产品的高级开发,用于故意释放或应对由NIAID A、B和C类优先病原体或新发传染病引起的自然发生的传染病暴发。该合同可能支持单个疫苗成分的配方和生产,以及稳定性测试、动物模型的非临床免疫原性和有效性测试、IND启用GLP毒理学、IND提交以及临床安全性和有效性评估。该项目的重点是为儿科人群开发急性弛缓性脊髓炎疫苗。
英文摘要
To support the advanced development of candidate products for use following the intentional release of or in response to naturally occurring outbreaks of infectious diseases caused by NIAID Category A, B, and C Priority Pathogens or emerging infectious diseases. This contract may support formulation and manufacture of the individual vaccine components, as well as stability testing, nonclinical immunogenicity and efficacy testing in animal models, IND enabling GLP toxicology, submission of an IND and clinical safety and efficacy evaluation. This project focuses on the development of an Acute Flaccid Myelitis vaccine for pediatric populations.
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DEVELOPMENT OF AN INTRANASAL VACCINE AGAINST GONORRHEA
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批准号:10710589
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项目类别:
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资助金额:$200.75万
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财政年份:2022
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负责人:DINJA OOSTERHOFF
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依托单位:
DEVELOPMENT OF AN INTRANASAL VACCINE AGAINST GONORRHEA
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批准号:10919579
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项目类别:
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资助金额:$75.68万
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财政年份:2022
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负责人:DINJA OOSTERHOFF
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依托单位:
Advanced Development of a Vaccine for Acute Flaccid Myelitis Associated with Enterovirus D68
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批准号:10436764
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项目类别:
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资助金额:$503.16万
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财政年份:2020
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负责人:DINJA OOSTERHOFF
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依托单位:
Advanced Development of a Vaccine for Acute Flaccid Myelitis Associated with Enterovirus D68
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批准号:10551063
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项目类别:
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资助金额:$19.45万
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财政年份:2020
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负责人:DINJA OOSTERHOFF
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依托单位:
Advanced Development of a Vaccine for Acute Flaccid Myelitis Associated with Enterovirus D68
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批准号:10269526
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项目类别:
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资助金额:$283.7万
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财政年份:2020
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负责人:DINJA OOSTERHOFF
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依托单位:
海外基金