ACTIVITY EFFECT ON SLEEP IN DEMENTIA

描述(改编自《调查者摘要》)：睡眠活动 节律紊乱是一种普遍的、致残的症状 痴呆症。睡眠障碍与夜间游荡可能是最单一的 将认知障碍(CI)老年人安置在养老院的常见原因。 医学治疗已被证明只有很小的效果，而且有严重的副作用。 效果。在五个受试者中的飞行员证明了个性化的 白天的活动干预改善了夜间的睡眠和影响， 并减少CI老年人的日间午睡。因此，其具体目标是 建议的研究是评估个性化活动的效果。 CI护理对夜间睡眠和心理健康的干预 表现出睡眠活动节律紊乱的家庭居民。这 研究将采用一次干预的前测-后测实验设计 另设1个对照组。在收集了五年的基线数据之后 天内，90名受试者将被随机分配到 个体化活动干预或给予对照组。目的 干预措施是用以下方式取代日间频繁的午睡 有意义的活动。在全面评估了居民的 当前的认知、身体、交流、感觉和情绪状态 和过去的利益，首席调查员将规定活动 对于试验组中的每个居民。个性化的示例 活动包括触觉和视觉刺激、艺术和 手工艺品和游戏。训练有素的项目护理助理将指导 每天至少干预一小时，每次15-30分钟， 一周七天，连续三周。干预的时间是 管理将基于白天小睡的模式在 基线，并观察居民的嗜睡情况。二十四小时 睡眠-觉醒模式将在第1-5天使用活动记录仪进行测量 基线，以及在第17-21天的干预期间。心理学 幸福感将使用痴呆症情绪图片测试进行三次评估 在基线期间和在个性化活动期间进行三次 干预。协方差分析，每个项目的平均基线得分 作为协变量的测量，将被用来确定是否 干预组和对照组不同。

DESCRIPTION (Adapted from the Investigator's Abstract): Sleep-activity rhythm disturbance is a prevalent, disabling symptom in patients with dementia. Disturbed sleep with night wandering may be the single most common cause for placing cognitively-impaired (CI) elders in nursing homes. Medical treatment has proven only minimally effective and has serious side effects. The pilot in five subjects demonstrated that an Individualized Activity Intervention in the daytime improved nocturnal sleep and affect, and reduced daytime napping in CI elders. Therefore, the specific aim of the proposed study is to evaluate the effect of an Individualized Activity Intervention on nocturnal sleep and psychological well-being of CI nursing home residents who demonstrate sleep-activity rhythm disturbance. This study will use a pretest-posttest experimental design with one intervention and one control group. Following the collection of baseline data for five days, the 90 subjects will be randomly assigned to receive either the Individualized Activity Intervention or to a control group. The purpose of the intervention is to replace frequent daytime napping episodes with meaningful activities. After a comprehensive assessment of the resident's current cognitive, physical, communication, sensory, and emotional status and past interests, the Principal Investigator will prescribe the activities for each resident in the experimental group. Examples of individualized activities include objects for tactile and visual stimulation, arts and crafts, and games. Trained Project Nursing Assistants will conduct the intervention for a minimum of one hour daily, in 15-30 minute sessions, seven days a week for three weeks. The time of day the intervention is administered will be based on the patterns of daytime napping during baseline, and observation of the resident for sleepiness. Twenty-four hour sleep-wake patterns will be measured using an actigraph on days 1-5 of baseline, and during the intervention on days 17-21. Psychological well-being will be assessed using the Dementia Mood Picture Test three times during baseline and three times during the Individualized activity Intervention. Analysis of covariance, with the mean baseline score for each measure serving as the covariate, will be used to determine whether the intervention and control groups differ.