Mechanisms of cartilage destruction and the effects of treatment in rheumatoid arthritis

类风湿性关节炎的软骨破坏机制及治疗效果

• 批准号: nhmrc : 113910
• 负责人: A/Pr Peter Youssef
• 金额: $ 15.99万
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2000
• 资助国家: 澳大利亚
• 起止时间: 2000-01-01 至 2002-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mechanisms-cartilage-destruction-rheumatoid-arthritis/97628
• 关键词: Mechanisms; cartilage; destruction; effects; treatment

Rheumatoid arthritis occurs in 1-3% of the population. It is associated with damage to joints causing pain and dificulty with mobility. There are several treatments for rheumatoid arthritis, none of which completely prevents this damage. This study looks at joint tissue and the ways in which damage occurs. It tries to understand why treatment works in some patients and not others. By doing this, the best ways of stopping joint damage will be determined. The study will also tell us the best ways of looking at whether treatment is working before joint damage occurs.

1-3% 的人口患有类风湿性关节炎。它与引起疼痛和活动困难的关节损伤有关。有多种治疗类风湿性关节炎的方法，但没有一种可以完全防止这种损害。这项研究着眼于关节组织以及损伤发生的方式。它试图理解为什么治疗对某些患者有效，而对另一些患者无效。通过这样做，将确定阻止关节损伤的最佳方法。该研究还将告诉我们在关节损伤发生之前观察治疗是否有效的最佳方法。