User-friendly Querying of Integrated Biological Database

方便用户查询综合生物数据库

• 批准号: 6703183
• 负责人: Zoe Lacroix
• 金额: $ 11.07万
• 依托单位: ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-30 至 2005-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6703183
• 关键词: Internet; computer human interaction; computer system design /evaluation; data collection methodology /evaluation; genetics; information systems; interdisciplinary collaboration; proteomics

DESCRIPTION (provided by applicant): Our proposed work seeks to design a query language adapted to scientists by combining additional scientific tasks such as mining, analyzing, searching, and browsing with traditional data manipulation tasks in a computational infrastructure that uses XML-based Web technology and database/mediation technology. This infrastructure will enable a user to express queries against multiple sources without explicit user knowledge of source-specific details including location, data structure, and computational interfaces and capabilities. The same infrastructure that enables the user to pose and execute such queries will also facilitate users to apply their expertise to filter, rank, and resolve inconsistencies in the query results. In the pilot phase, we achieve these objectives through the following research aims: Aim 1: Design a user-friendly query language adapted to scientific tasks. Aim 2: Design a system that integrates scientific resources: data and applications to support scientific queries. The pilot phase will identify and resolve specific problems to scientific querying focusing on biological queries. Should the pilot phase be funded, the investigator will seek continuing support for development through a research project grant R01. The aims of the continuing support will be the development of the mediation platform designed at the pilot phase. It will include: XML Enabled Wrapper Generation, incorporation of XML wrappers into a mediation platform, and testing and evaluation. A team of computer scientists, biologists and physicians will be constituted for the research project grant R01.

描述（由申请人提供）： 我们提出的工作旨在设计一种适合科学家的查询语言，通过将额外的科学任务（例如挖掘、分析、搜索和浏览）与使用基于 XML 的 Web 技术和数据库/中介技术的计算基础设施中的传统数据操作任务相结合。 该基础设施将使用户能够表达针对多个源的查询，而无需用户明确了解特定于源的详细信息，包括位置、数据结构以及计算接口和功能。使用户能够提出和执行此类查询的相同基础设施也将有助于用户应用他们的专业知识来过滤、排名和解决查询结果中的不一致。在试点阶段，我们通过以下研究目标来实现这些目标： 目标 1：设计一种适合科学任务的用户友好的查询语言。 目标 2：设计一个集成科学资源的系统：支持科学查询的数据和应用程序。 试点阶段将识别并解决以生物学查询为重点的科学查询的具体问题。如果试点阶段获得资助，研究人员将通过研究项目拨款 R01 寻求持续的开发支持。持续支持的目标将是开发试点阶段设计的调解平台。它将包括：支持 XML 的包装器生成、将 XML 包装器纳入中介平台以及测试和评估。 R01 研究项目拨款将组成一个由计算机科学家、生物学家和医生组成的团队。