Cell Biology of the Immune Response

免疫反应的细胞生物学

• 批准号: 6583493
• 负责人: IRA S MELLMAN
• 金额: $ 0.5万
• 依托单位: KEYSTONE SYMPOSIA
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-01-15 至 2003-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6583493
• 关键词: T lymphocyte; cell biology; dendritic cells; immunology; meeting /conference /symposium; travel

DESCRIPTION (provided by applicant): It is increasingly clear that fundamental problems in the immune response must be understood in terms of basic cellular mechanisms involving membrane traffic, intracellular transport, proteolysis, cell polarity, cytoskeletal dynamics, cell motility, membrane domain organization, and signal transduction. The overall goal of the meeting, "Cell Biology of the Immune Response", is to explore this emerging interface between immunology and cell biology. Our Specific Aims include: 1) Bringing together experts in the relevant areas of cell biology and immunology who have the interest in learning what each field has to offer the other. 2) Focus the meeting on the topics related to dendritic cell function and T cell stimulation, to synergize this conference with a concurrent conference entitled "Dendritic Cells, Interfaces with Immunobiology". 3) Provide an environment for young immunologists and cell biologists to come together early in theircareers to encourage scientific development at this critical emerging interface. 4) To explore how the cellular basis of the immune response contributes to the pathogenecity of and potential immunological therapy for cancer and infectious disease.

描述(由申请人提供)：越来越清楚的是，免疫反应中的基本问题必须从涉及膜运输、细胞内运输、蛋白质分解、细胞极性、细胞骨架动力学、细胞运动性、膜域组织和信号转导等基本细胞机制的角度来理解。这次会议的总体目标是“免疫反应的细胞生物学”，旨在探索免疫学和细胞生物学之间的这一新兴接口。我们的具体目标包括：1)将细胞生物学和免疫学相关领域的专家聚集在一起，他们有兴趣了解每个领域都能为另一个领域提供什么。2)将会议重点放在与树突状细胞功能和T细胞刺激相关的主题上，以配合本次会议，同时举办题为“树突状细胞与免疫生物学的接口”的会议。3)为年轻的免疫学家和细胞生物学家提供一个环境，让他们在职业生涯的早期走到一起，鼓励在这一关键的新兴界面上的科学发展。4)探讨免疫反应的细胞基础如何在癌症和传染病的发病机制和潜在的免疫治疗中起作用。