New Sterilization Method for Contact Lenses and Cases
New Sterilization Method for Contact Lenses and Cases
批准号:
6552028
负责人:
DON B ELROD
金额:
$10.47万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2003
资助国家:
美国
项目状态:
已结题
起止时间:
2003-09-01 至 2004-08-31
中文摘要
描述(由申请人提供):隐形眼镜(CLs)是一种成功的视力控制形式,全球戴隐形眼镜的人数已增至8500万,全国戴隐形眼镜的人数已增至3200万。许多CL使用者并没有意识到潜在的风险。佩戴CL最严重的并发症是微生物性角膜炎引起的危及视力的角膜溃疡。据估计,美国每年发生3万例MK病例。使用CL,特别是长时间佩戴的镜片,是MK的一个重要危险因素。美国眼科学会指出,“在MK bbb患者中,CL使用者中CL消毒不充分、CL储存盒污染和CL溶液污染的发生率很高。”为了降低与cl相关的MK风险,迫切需要改进护理产品和用户遵守推荐的晶状体护理制度。只有25- 35%的隐形眼镜佩戴者遵循了所有推荐的镜片护理说明。针对CLs和晶状体病例提出了一种新的灭菌方法,通过简化他们的晶状体护理制度,提高患者的依从性,并提供比现有消毒剂显著的优势——在低两个数量级的浓度下,所提出的杀菌剂比过氧化氢对更广泛的生物更有效。
英文摘要
DESCRIPTION (provided by applicant): Contact lenses (CLs) are a successful form of vision control, and the number of people wearing CLs has swelled to 85 million worldwide-32 million nationwide. Many CL wearers are unaware of the potential risks. The most serious complication of CL wear is sight threatening corneal ulceration caused by microbial keratitis (MK). An estimated 30,000 cases of MK occur annually in the US. The use of CLs, especially extended wear lenses, is a significant risk factor for MK. The American Academy of Ophthalmology states, "High prevalence of inadequate CL disinfection, CL storage-case contamination, and contaminated CL solutions among CL users have been reported <in patients with MK>.' To reduce the risk of CL-associated MK, improvements in tens care products and users compliance with recommend lens care regimes are desperately needed. Only 25-35 percent of CL wearers follow all of their recommended lens care instructions. A new sterilization method is proposed for CLs and lens cases that should improve patient compliance by simplifying their lens care regime and offer significant advantages over current disinfectants-at two orders of magnitude lower concentration the proposed biocide is more effective than hydrogen peroxide against a broader range of organisms.
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会议论文
Antimicrobial Dressings for Burn Wound Infection Control
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批准号:6688012
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项目类别:
-
资助金额:$12.59万
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财政年份:2003
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负责人:DON B ELROD
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依托单位:
海外基金