Int'l Center for Indigenous Phytotherapy Studies--TICIPS
Int'l Center for Indigenous Phytotherapy Studies--TICIPS
批准号:
6805743
负责人:
William Robert Folk
金额:
$11.48万
依托单位国家:
美国
项目类别:
财政年份:
2003
资助国家:
美国
项目状态:
已结题
起止时间:
2003-09-25 至 2006-03-31
关键词:
AIDSAfricaalternative medicinebenign prostate hyperplasiaclinical researchclinical trialscooperative studydrug screening /evaluationhigh performance liquid chromatographyhuman subjecthuman therapy evaluationmedicinal plantsmicroarray technologypatient oriented researchpharmacokineticspolymerase chain reactionprostate neoplasmsprostate preneoplastic statetraining
中文摘要
描述(由申请者提供):密苏里哥伦比亚大学(MU)将与南非西开普大学(UWC)和圣路易斯密苏里植物园(Mobot)合作成立国际土著植物疗法研究中心(TICIPS)。墨尔本大学在卫生保健质量改进和生物医学科学方面拥有出色的研究和教育项目,包括墨尔本大学植物营养素和植物化学研究中心。UWC拥有杰出的CAM研究和教育项目,特别是在药用植物方面,并与使用传统治疗师的南非人和南非政府建立了广泛的联系。Mobot是北美的非洲植物研究中心。在墨尔本大学和UWC之间长达17年的关系的基础上,寻求资金用于规划工作,以确定TICIPS的使命、愿景和战略计划;发展行政基础设施,以支持合作研究和联合教育活动;并评估建立补充和替代医学综合国际研究中心所需的资源和需求。在第一阶段,将建立健全的行政结构和政策,以确保遵守两国在人体和动物研究、财务披露、利益冲突和知识产权方面的法规。试点将用于展示合作伙伴的能力,并启动研究和培训工作,以实现NCCAM的目标。Pilot 1将启动Sutherlandia水果香的I期临床试验,Sutherlandia水果香是一种用于阻止艾滋病患者消瘦的草药。Pilot 2将研究Tulbagia Violacea作为治疗念珠菌病的本土植物疗法。Pilot 3将评估低氧植物疗法治疗前列腺增生症和癌症。这些项目的规划和执行以及行政核心的发展将为国际研究及补充和替代医学中心奠定基础。
英文摘要
DESCRIPTION (provided by applicant): The University of Missouri-Columbia (MU) will form the International Center for Indigenous Phytotherapy Studies (TICIPS) in collaboration with the University of Western Cape, South Africa (UWC) and the Missouri Botanical Garden, St. Louis (MOBOT). MU has outstanding research and educational programs in health care quality improvement and biomedical sciences, including the MU Center for Phytonutrient and Phytochemical Studies. UWC has outstanding CAM research and educational programs, especially in medicinal plants, and extensive ties with South Africans that use traditional healers, and with the South African government. MOBOT is the North American center for research of African flora. Funds are sought for a planning effort, building upon a 17-year relationship between MU and UWC, to define the mission, vision and strategic plan for TICIPS; to develop the administrative infrastructure to support collaborative research studies and joint educational activities; and to assess resources and needs required for the establishment of a comprehensive international center for research on complementary and alternative medicine. During Phase I, sound administrative structures and policies will be established to ensure compliance with both countries' regulations on the conduct of research with human subjects and animal subjects, financial disclosure, conflict of interest and intellectual property rights. The pilots will serve to demonstrate the capabilities of the partners and to initiate research and training efforts that fulfill the goals of NCCAM. Pilot 1 will open a Phase I clinical trial on Sutherlandia frutscens, an herbal used to deter wasting in AIDS patients. Pilot 2 will study Tulbaghia violacea as an indigenous phytotherapy for candidiasis. Pilot 3 will evaluate Hypoxis hemerocallidea phytotherapies for prostate hyperplasia and cancer. Planning and execution of these projects and the development of an administrative core will lay the foundation for an International Center for Research and Complementary and Alternative Medicine.
期刊论文(4)
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Abandonment of antiretroviral therapy: a potential barrier to scale-up in sub-Saharan Africa.
放弃抗逆转录病毒治疗:撒哈拉以南非洲扩大规模的潜在障碍。
DOI:
--
发表时间:
2008
期刊:
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
影响因子:
--
作者:
[Reid,StewartE, Mulenga,LloydB, Folk,WilliamR, Tambatamba,BushimbwaC, Chi,BenjaminH]
通讯作者:
Chi,BenjaminH
Cycloartane glycosides from Sutherlandia frutescens.
来自 Sutherlandia frutescens 的环阿麻苷。
DOI:
10.1021/np800328r
发表时间:
2008-10
期刊:
JOURNAL OF NATURAL PRODUCTS
影响因子:
5.1
作者:
[Fu, Xiang, Li, Xing-Cong, Smillie, Troy J., Carvalho, Paulo, Mabusela, Wildfred, Syce, James, Johnson, Quinton, Folk, William, Avery, Mitchell A., Khan, Ikhlas A.]
通讯作者:
Khan, Ikhlas A.
DOI:
10.1371/journal.pctr.0020016
发表时间:
2007-04-27
期刊:
PLoS clinical trials
影响因子:
--
作者:
[Johnson, Quinton, Syce, James, Folk, William R]
通讯作者:
Folk, William R
Efficacy of Artemisia afra phytotherapy in experimental tuberculosis.
黑蒿植物疗法对实验性结核病的疗效。
DOI:
10.1016/s1472-9792(09)70009-5
发表时间:
2009
期刊:
Tuberculosis (Edinburgh, Scotland)
影响因子:
--
作者:
[Ntutela,Siyabulela, Smith,Pete, Matika,Lungile, Mukinda,James, Arendse,Hiram, Allie,Nasiema, Estes,DMark, Mabusela,Wilfred, Folb,Peter, Steyn,Lafras, Johnson,Quinton, Folk,WilliamR, Syce,James, Jacobs,Muazzam]
通讯作者:
Jacobs,Muazzam
Linking Science, Mathematics and Literacy for All Learners
-
批准号:10592425
-
项目类别:
-
资助金额:$26.12万
-
财政年份:2022
-
负责人:William Robert Folk
-
依托单位:
Linking Science, Mathematics and Literacy for All Learners
-
批准号:10450437
-
项目类别:
-
资助金额:$26.88万
-
财政年份:2022
-
负责人:William Robert Folk
-
依托单位:
Strengthening Middle School Science and Health Education for Diverse Learners by Linking Grade-Level Reading of Complex Texts and Inquiry
-
批准号:9303069
-
项目类别:
-
资助金额:$26.83万
-
财政年份:2017
-
负责人:William Robert Folk
-
依托单位:
Strengthening Middle School Science and Health Education for Diverse Learners by Linking Grade-Level Reading of Complex Texts and Inquiry
-
批准号:10252846
-
项目类别:
-
资助金额:$24.22万
-
财政年份:2017
-
负责人:William Robert Folk
-
依托单位:
Phased Exploratory Clinical Studies of Harpagophytum procumbens' Impact upon the Biological Signature of inflammatory Osteoarthritis.
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批准号:9771124
-
项目类别:
-
资助金额:$29.51万
-
财政年份:2016
-
负责人:William Robert Folk
-
依托单位:
Phased Exploratory Clinical Studies of Harpagophytum procumbens’ Impact upon the Biological Signature of Inflammatory Osteoarthritis
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批准号:9095048
-
项目类别:
-
资助金额:$19.12万
-
财政年份:2016
-
负责人:William Robert Folk
-
依托单位:
Core 2 - Clinical Trials Core
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批准号:7048954
-
项目类别:
-
资助金额:$8.41万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
Core 4 - Communication Core
-
批准号:7048958
-
项目类别:
-
资助金额:$11.09万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
Administrative Core
-
批准号:7048953
-
项目类别:
-
资助金额:$46.53万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
Core 3 - Traditional Healers Core
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批准号:7048956
-
项目类别:
-
资助金额:$7.29万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
Core 5 - Phytochemistry & Biodiversity Core
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批准号:7048959
-
项目类别:
-
资助金额:$9.07万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
Replication of BK DNA in Murine Cells and Extracts
-
批准号:6850306
-
项目类别:
-
资助金额:$16.1万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
Project 1 - Phase I/II Clinical Trial of L. frutescens in HIV-infected adults
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批准号:7048945
-
项目类别:
-
资助金额:$15.28万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
TICIPS: HIV/AIDS, Secondary Infections and Immune Modul*
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批准号:7502645
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项目类别:
-
资助金额:$79.66万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
TICIPS: HIV/AIDS, Secondary Infections and Immune Modulation
-
批准号:7287874
-
项目类别:
-
资助金额:$101.56万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
TICIPS: HIV/AIDS, Secondary Infections and Immune Modul*
-
批准号:7021683
-
项目类别:
-
资助金额:$90.72万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
Replication of BK DNA in Murine Cells and Extracts
-
批准号:7034567
-
项目类别:
-
资助金额:$18.18万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
TICIPS: HIV/AIDS, Secondary Infections and Immune Modul*
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批准号:7939040
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项目类别:
-
资助金额:$15.0万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
TICIPS: HIV/AIDS, Secondary Infections and Immune Modul*
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批准号:7127190
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项目类别:
-
资助金额:$101.09万
-
财政年份:2005
-
负责人:William Robert Folk
-
依托单位:
Int'l Center for Indigenous Phytotherapy Studies--TICIPS
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批准号:6738266
-
项目类别:
-
资助金额:$16.06万
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财政年份:2003
-
负责人:William Robert Folk
-
依托单位:
海外基金