GENE THERAPY RESOURCE PROGRAM (GTRP): PHARMACOLOGY AND TOXICOLOGY CORE LABORATORY SCIENTIFIC ACTIVITIES

基因治疗资源计划 (GTRP)：药理学和毒理学核心实验室科学活动

• 批准号: 10725215
• 负责人: CHRISTOPHER DENMAN
• 金额: $ 5.96万
• 依托单位: LOVELACE BIOMEDICAL & ENVIRONMENTAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-12-19 至 2022-12-18
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10725215
• 关键词: Animal Model; Animals; Biodistribution; Biological Assay; Contractor; Emerging Technologies; Funding; Gene Transduction Agent; Laboratories; Pharmacology and Toxicology; Regulation; Research Personnel; Resources; Rodent; Technology; Testing; gene therapy; good laboratory practice; new technology; nonhuman primate; pre-clinical; programs; vector

The Pharmacology/Toxicology Core Laboratory conducts preclinical vector pharmacology/toxicology testing and biodistribution studies, using all types of gene therapy vectors in small and/or large animals in accordance with Good Laboratory Practices (GLP) and all applicable Federal, State, and local regulations for use by GTRP investigators.

药理学/毒理学核心实验室根据药物非临床研究质量管理规范（GLP）和所有适用的联邦、州和地方法规，在小型和/或大型动物中使用所有类型的基因治疗载体进行临床前载体药理学/毒理学试验和生物分布研究，供GTRP研究者使用。