Replacing an Animal Resource Facility Cage Washer.

描述（由申请人提供）：克莱顿大学是一所独立的综合性耶稣会大学，位于内布拉斯加州奥马哈。克莱顿大学及其医学院（CUSOM）的使命是发展和促进对人类健康以及疾病的原因、治疗和预防的理解。为此，克莱顿大学通过扩建和翻新现有建筑和改善五个核心设施，大力扩展其基础研究能力。克莱顿大学及其研究人员意识到，最先进的动物资源设施对于任何现代研究型机构的持续成功至关重要。在过去的几年里，克莱顿大学已经投资了80万美元来扩大和提高老鼠的携带能力，将我们的笼子系统换成了现代的索伦架，并投资了安全柜。我们还将我们的接收区现代化，使之成为一个屏障设施，以便快速、安全地进口新的小鼠品系。克莱顿大学动物设施的这些改进已于2005年获得AAALAC认证。对于这笔G20赠款，我们建议更换我们1.7万平方英尺动物资源设施中过时的笼式洗衣机。具体地说，我们通过这项提案寻求财政支持，为将通过克莱顿大学购买的新笼式洗衣机的住房翻新一个区域。动物资源设施研究区域的拟议改造是克莱顿正在进行的科学综合大楼的多阶段建设，改造和扩建的一个组成部分。拟议的动物资源设施改造的长期目标是提高我们当前的研究生产力，并为当前和未来的尖端生物医学研究提供所需的动物资源。

DESCRIPTION (provided by applicant): Creighton University is an independent, comprehensive Jesuit university located in Omaha, Nebraska. The mission of the Creighton University and its School of Medicine (CUSOM) is to develop and promote understanding of human health and the causes, treatments, and prevention of disease. To this end, Creighton University has been engaged in a major extension of its basic research capacity by expanding and renovating existing buildings and improving five core facilities. Creighton University, and this research faculty, are aware that state-of-the-art animal resource facilities are essential for the continued success of any modern research oriented institution. Creighton University has over the last few years invested $800,000 to expand and improve the mouse carrying capacity by changing our cage system to modern Thoren racks and investing in safety cabinets. We have also modernized our receiving area into a barrier facility for rapid and safe import of new mouse lines. These improvements in the Creighton University animal facility have let to AAALAC certification as of 2005. For this G20 grant we propose to replace the outdated cage washer of our 17,000 square-foot Animal Resource Facility. Specifically, we seek with this proposal financial support to renovate an area for housing of the new cage washer that will be purchased through Creighton University. This proposed renovation of the research areas of the Animal Resource Facility is an integrated part of Creighton's ongoing multi-phased construction, remodeling, and expansion of the Science Complex. The long-term objective for the proposed Animal Resource Facility renovation is to enhance our current research productivity and to provide the animal resources needed for current and future cutting-edge, NIH funded biomedical research. The specific aim of the project is to replace the existing outdated cage washer with a state-of-the-art system. Creighton University will purchase the cage washer and the autoclave. We hope to obtain through this application the support to renovate the existing space in the animal facility to house and operate effectively this new cage washer to generate a nucleus for an already planned barrier facility to house the many transgenic mouse lines already at Creighton University and the additional ones we will soon have.