Leveraging mHealth to Increase Health Equity among Black Individuals with Opioid Use Disorder and Commonly Occurring Mental Health Disorders

利用移动医疗提高患有阿片类药物使用障碍和常见心理健康障碍的黑人的健康公平

• 批准号: 10722105
• 负责人: Hannah Szlyk
• 金额: $ 18.05万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-15 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10722105
• 关键词: Achievement; Address; Adherence; Anxiety; Applied Skills; Area; Attitude; Award; Black American; Black Populations; Black race; Caring; Cessation of life; Cities; Client; Clinical; Clinical Trials; Control Groups; Data; Development; Discrimination; Economics; Elements; Environment; Evidence based treatment; Exposure to; Face; Feedback; Focus Groups; Fostering; Foundations; Future; Goals; Health education; Healthcare; Inequity; Intervention; Interview; Life; Location; Mental Depression; Mental Health; Mental disorders; Mentored Research Scientist Development Award; Mentors; Mentorship; Methodology; Methods; Minority Groups; Missouri; Opioid; Outcome; Overdose; Participant; Persons; Pharmaceutical Preparations; Population; Prevention strategy; Provider; Public Health; Race; Randomized; Randomized, Controlled Trials; Recovery; Recovery Support; Reporting; Research; Research Activity; Research Methodology; Research Personnel; Research Project Grants; Resources; Risk Factors; Scientist; Structural Racism; Structure; Telephone; Testing; Text Messaging; Therapeutic Intervention; Training; Training Activity; United States; United States Dept. of Health and Human Services; United States National Institutes of Health; United States Substance Abuse and Mental Health Services Administration; Universities; Washington; acronyms; addiction; barrier to care; career; career development; clinical care; community based care; cost effective intervention; depressive symptoms; design; digital; digital treatment; experience; health care availability; health equity; health equity promotion; high risk; implementation facilitators; implementation science; implementation strategy; improved; innovation; mHealth; medical schools; medication for opioid use disorder; meetings; metropolitan; mortality; motivational enhancement therapy; opioid epidemic; opioid mortality; opioid overdose; opioid policy; opioid use disorder; overdose prevention; overdose risk; peer; peer support; prevent; primary outcome; psychoeducation; psychoeducational; response; secondary outcome; skill acquisition; skills; sobriety; social factors; social stigma; structural determinants; substance use; substance use treatment; success; symposium; tool; treatment adherence; uptake; usability; user centered design

Project Summary The overarching goal of this Research Scientist Development Award (K01) is to provide Dr. Hannah Szlyk with the training and research activities needed to become an independent researcher who develops, tests, and implements cutting-edge digital therapeutic interventions that can promote health equity in recovery from opioid use disorder (OUD) plus commonly occurring mental disorders (COMD). This application outlines an integrated training and research plan that will provide Dr. Szlyk with the skills needed to achieve her career goal. Under the mentorship of experts in clinical trials, health equity, implementation science, user-centered design, and OUD research, Dr. Szlyk’s training will focus on the following key areas: (1) clinical trial methodology (Dr. Esther Lu; (2) implementation science and user-centered design (Drs. Patricia Cavazos-Rehg and Emily C. Williams); and (3) health equity in addictions and mental health (Dr. Darrell Hudson). Training in these three areas will be achieved through didactic and applied activities, participation in national conferences and institutes, and mentoring meetings. Dr. Szlyk will apply the skills acquired during the training activities to conduct a research project to appropriately adapt and test an mHealth intervention for Black Americans with OUD plus COMD. Rates of opioid-related deaths continue to rise among Black Americans in the United States. These deaths are often concentrated in medium-sized metropolitan cities, like St. Louis, Missouri, where this research is set. Yet, few interventions are developed to fit the unique needs of Black clients; none address their heightened overdose risk often compounded by COMD which decreases likelihood for recovery success. Also, Black individuals experience significant barriers to life saving OUD treatments, like medication for OUD (MOUD), because of structural racism. To address this gap, the K01 research project will integrate public health critical race praxis, implementation science, and user-centered design strategies to appropriately adapt an mHealth intervention for Black Americans with OUD plus COMD. The central hypothesis is that adaptations to the mHealth intervention will improve engagement and usability among Black participants, improve adherence to MOUD, and impact decreases in COMD. This research will address key gaps in treatment by 1) adapting an mHealth intervention for Black individuals with OUD plus COMD; 2) identifying barriers and facilitators to implementing an mHealth intervention among stakeholders who serve Blacks with OUD plus COMD; 3) examining the preliminary efficacy of an adapted mHealth intervention. These data will inform the design of a larger RCT for a future R01 application. Dr. Szlyk’s training and proposed research will be carried out in the outstanding intellectual environment of Washington University School of Medicine, which will provide her with a multitude of resources to meet her goals.

项目摘要 该研究科学家发展奖（K 01）的总体目标是为Hannah Szlyk博士提供 培训和研究活动需要成为一个独立的研究人员谁开发，测试， 实施尖端的数字治疗干预措施，可以促进从 阿片类药物使用障碍（OUD）加上常见精神障碍（COMD）。此应用程序概述了 综合培训和研究计划，将为Szlyk博士提供实现其职业生涯所需的技能 目标.在临床试验专家的指导下，健康公平，实施科学，以用户为中心 设计和OUD研究，Szlyk博士的培训将集中在以下关键领域：（1）临床试验 方法论（Esther Lu博士）;（2）实施科学和以用户为中心的设计（Patricia Cavazos-Bogg博士 和艾米丽C.威廉姆斯）;（3）成瘾和心理健康的健康公平（达雷尔哈德逊博士）。培训 将通过教学和应用活动、参加国家 会议和研究所，以及指导会议。Szlyk博士将应用在培训中获得的技能 开展研究项目的活动，以适当调整和测试黑人的移动健康干预措施 OUD加上COMD的美国人。阿片类药物相关死亡率在美国黑人中继续上升， 美国的这些死亡通常集中在中等规模的大城市，如圣路易斯， 密苏里州，这个研究的地方。然而，很少有干预措施被开发出来，以满足黑人的独特需求。 客户;没有解决他们的过量风险增加，往往由COMD，降低可能性 恢复成功。此外，黑人个体在挽救生命的OUD治疗方面遇到了重大障碍， 药物治疗OUD（MOUD），因为结构性种族主义。为了解决这一差距，K 01研究项目将 整合公共卫生关键种族实践、实施科学和以用户为中心的设计策略， 适当地调整移动健康干预与OUD加COMD的美国黑人。中央 一种假设是，对移动健康干预的适应将提高黑人的参与度和可用性。 参与者，提高对MOUD的遵守，并影响COMD的减少。这项研究将解决关键 治疗差距：1）针对OUD + COMD黑人个体调整移动健康干预措施; 2） 确定在提供服务的利益相关者中实施移动健康干预措施的障碍和促进因素 OUD加COMD的黑人; 3）检查适应性移动健康干预的初步疗效。 这些数据将为未来R 01应用的更大RCT设计提供信息。斯莱克医生的训练 拟议中的研究将在华盛顿大学杰出的学术环境中进行 医学院，这将为她提供多种资源，以满足她的目标。