Evaluation of a Remotely-Delivered Behavioral Intervention for Post-Bariatric Surgery Weight Regain

减肥手术后体重恢复的远程行为干预的评估

• 批准号: 10735424
• 负责人: Lauren E Bradley
• 金额: $ 69.25万
• 依托单位: TEMPLE UNIV OF THE COMMONWEALTH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10735424
• 关键词: Address; Adherence; Aftercare; Bariatrics; Behavior Control; Behavior Therapy; Behavioral; Biological Markers; Body Weight; Body Weight decreased; Caring; Cellular Phone; Clinical Treatment; Control Groups; Diabetes Mellitus; Eating; Eating Behavior; Ecological momentary assessment; Educational process of instructing; Elements; Energy Intake; Enrollment; Evaluation; Frequencies; Gastrectomy; Gastric Bypass; Health; Health Benefit; Hunger; Hypertension; Individual; Instruction; Interruption; Intervention; Life Style Modification; Measures; Mediating; Medical; Morbid Obesity; Operative Surgical Procedures; Outcome; Participant; Patients; Pattern; Persons; Physical activity; Physiological; Postoperative Care; Postoperative Period; Procedures; Randomized; Recommendation; Recurrence; Reporting; Research; Risk; Telephone; Testing; Time; Treatment Efficacy; Weight; Weight maintenance regimen; Work; active method; bariatric surgery; behavior test; clinically significant; comorbidity; comparison control; comparison intervention; craving; design; dietary; effective therapy; efficacy evaluation; efficacy testing; experience; follow-up; food craving; improved; innovation; mindfulness; negative affect; novel; novel strategies; obesity treatment; online delivery; online version; patient engagement; patient population; pilot trial; post intervention; programs; remote delivery; response; secondary outcome; skills; theories; weight maintenance

PROJECT SUMMARY/ABSTRACT The proposed study is designed to evaluate the efficacy of a remotely-delivered, acceptance-based behavioral intervention (ABTi) for individuals demonstrating weight regain after bariatric surgery by comparing it to a Control condition. The current study aims to: 1) evaluate ABTi's efficacy on weight outcomes compared to Control; 2) evaluate ABTi's efficacy on secondary outcomes including improvements in eating behaviors, physical activity, and medical conditions compared to Control; 3) test proposed mechanisms of action, including evaluating a) if changes in hypothesized active ingredients in ABTi mediate differences in weight outcomes between conditions and b) if the association between eating behavior and subjective internal states (i.e., hunger, cravings, urges, negative affect) will weaken in ABTi compared to Control. Patients 6 to 48 months out from surgery who have regained >5% of their weight will be randomized to ABTi or Control (n=200). Assessments willbe conducted at baseline, 3, 6 (end of active treatment), and 12 months (follow up) after enrollment. Developing innovative interventions to reverse postoperative weight regain is crucial to maintain the health benefits of surgery in this growing population of patients not experiencing optimal postoperative results.

项目总结/文摘