Risk of Blood Borne Transmission of CJD

克雅氏病血源性传播的风险

• 批准号: 7498043
• 负责人: SHIMIAN ZOU
• 金额: $ 9.2万
• 依托单位: AMERICAN NATIONAL RED CROSS
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-01 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7498043
• 关键词: Risk; Blood; Borne; Transmission; CJD

PROVIrlED. Purpc,se:The purposeof thisprogramisto continuean active, nationwidestudybegunin 1995of recipients of bloodproductsfrom donorswho subsequentlydevelopedclassicor possiblyvariantCJD to assessthe risk of"bloodbornetransmissionof these diseasesin the UnitedStates. Research Objectives:To systematicallycollectdata thatwillhelpdeterminewhetherclassicor variantCJD is beingtransmittedby bloodand bloodcomponentsinthe UnitedStates. Methods:The studywillbe conductedas follows: ¿ Maintainand increasecollaborativerelationshipswithUS bloodbanksto identifythe classicCJD blood donors andpotentiallythevariantCJD blooddonorsinthe UnitedStates andgatheravailable,relevant, medicalanddemographicinformationon suchdonors. ¿ Trace classicand variantCJD donorbloodcomponentstofinaldisposition. ¿ Maintainand enhancecollaborativerelationswithfinaldispositionsites andcollectvitalstatistics informationfrom pre-existingrecordsaboutrecipientsof the classicor variantCJD bloodcomponents. ¿ Maintainstudyinformationaboutthe recipientsofthe bloodcomponentsfrom classicCJD donorswho were previouslyidentifiedinthisstudyandcontinuetomonitorthese recipients'vitalstatus,includingthe causesof deathshouldtheydie. ¿ Developa planthat will(a) Searchnational,State,and localorganizationsdatabasesto matchvital static;ticsandcauses of deathfor thecomponentrecipients,includingutilizingnon-NationalDeath Index databasesto confirmthevital statusofthe componentrecipientsand (b) assessthe riskof blood-borne transmissionofCJD. Publishanddisseminateresultsof thestudy.

PROVIrlED。