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Achieving successful treatment outcomes among adolescents and pregnant/postpartum women living with HIV in Kenya

在肯尼亚感染艾滋病毒的青少年和孕妇/产后妇女中取得成功的治疗结果

基本信息

批准号：
10760594
负责人：
Lisa Lynn Abuogi
金额：
$ 19.16万
依托单位：
UNIVERSITY OF COLORADO DENVER
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-14 至 2028-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10760594
关键词：
AIDS prevention Address Adherence Adolescent Adolescent and Young Adult Adult Award Behavior Therapy Behavioral Sciences Caring Child Clinic Collaborations Colorado Counseling Dedications Disparity Electronics Enrollment Ensure Extramural Activities Failure Focus Groups Funding Goals HIV Health Impact evaluation Infrastructure Intervention Intervention Studies Interview Kenya Knowledge Mentors Mentorship Midcareer Investigator Award in Patient-Oriented Research Modeling NIH Office of AIDS Research Outcome Parents Participant Patients Pediatric Hospitals Pediatrics Perception Persons Physician Executives Physicians Population Postpartum Period Postpartum Women Pregnant Women Prevention program Productivity Provider Psychosocial Assessment and Care Qualifying Randomized Readiness Research Research Activity Research Personnel Research Priority Resource-limited setting Sampling Science Scientist Site Structure Time Training Treatment Failure Treatment outcome United States National Institutes of Health Universities Viral Visit Vulnerable Populations Woman Work Youth antenatal care antiretroviral therapy care outcomes career empowerment evidence base experience global health health disparity implementation science improved innovation mid-career faculty multidisciplinary next generation patient oriented research peer peer support pregnant prevent primary outcome recruit resilience skills standard of care success treatment risk uptake young adult young woman

项目摘要

Project Summary Overview: This K24 mid-career investigator award in patient-oriented research and mentorship proposes to expand the research and mentorship activities of a highly qualified candidate, Dr. Lisa Abuogi, focused on improving HIV and health outcomes for people living with HIV in high burden, low resource settings. Candidate: Dr. Abuogi is a physician-scientist trained in pediatrics, global health, and HIV and an Associate Professor at the University of Colorado Denver (UCD). She is also a Senior Investigator in the UCD Center for Global Health and Medical Director of the Children's Hospital HIV Prevention Program. Dr. Abuogi conducts patient-oriented research to address disparities in HIV health outcomes, including retention in care and viral suppression, among pregnant women, adolescents and children living with HIV. She has a sustained track record of extramural funding and demonstrated dedication to successful mentorship of new investigators. Mentoring Plan: Dr. Abuogi has a demonstrated commitment to highly successful mentorship of a diverse group of mentees. She has the ability to recruit multidisciplinary mentees from a wide range of research collaborations and networks, a structured approach to ensure high quality mentorship, and a commitment to build the next generation of investigators committed to research aimed addressing knowledge gaps and at improving HIV outcomes. Research Plan: Dr. Abuogi's proposed research activities address NIH's Office of AIDS Research Priority Research agenda in Cross Cutting research that includes implementation and behavioral sciences, health disparities, and training and capacity building. Leveraging her ongoing NIH-funded research evaluating behavioral interventions to improve HIV care outcomes for both pregnant/postpartum and on 1, viral women and adolescents young adults living with HIV (AYA), Dr. Abuogi proposes innovative new patient-oriented research focused the sustainable impact f interventions aimed a improving engagement in care and viral suppression. In Aim Dr. Abuogi will examine the effect of short-term peer navigation on long-term sustained re-engagement and suppression in AYA on antiretroviral treatment after navigation is discontinued. In Aim 2, o t determine the impact of behavioral interventions on care transitions in these populations. Finally, in Aim 3, she will explore the perceptions of patients and LHW on how the interventions support treatment success as well as unintended consequences of peer-led interventions to inform iterative adaptations of these interventions. proposed evidence-based provide The newly research described in this application will expand our understanding of the sustainable impact of interventions aimed at improving treatment outcomes for vulnerable populations with HIV and research opportunities for new mentees.

项目总结