Interventions that Address Structural Racism to Reduce Kidney Health Disparities Research Coordinating Center

项目摘要 认识到结构性种族主义对少数群体肾脏健康的重大影响， NIH 正在创建一个新的联盟，重点关注解决结构性种族主义的干预措施，以减少 肾脏健康差异。该联盟将汇集来自六个干预措施的研究团队 开展社区参与干预研究的网站，以解决结构性种族主义并减少 肾脏健康和疾病范围内的差异。我们建议担任研究 联盟协调中心 (RCC)。杜克大学 RCC 将利用广泛的机构 杜克大学提供行政领导和研究的资源和专业知识 协调，确保联合体的无缝运作和联合体的成功开展 研究；支持联盟严格的数据收集、数据管理和数据分析 研究；促进肾脏领域的研究合作、能力建设和劳动力多元化 健康公平研究。三个紧密结合的核心将领导 RCC 的核心活动。的 行政和协调核心将为以下人员提供行政、运营和后勤支持： 该联盟，包括协调会议、开发安全的基于网络的通信 和协作平台，支持项目管理和监管提交， 管理辅助研究的机会库，并不断评估和加强 联合体经营。数据管理和分析核心将有助于最终设计 联合体研究，为多站点联合体研究提供数据监测，并支持统计 多站点联合体研究分析以及跨区域通用数据元素的汇总分析 财团。协作和社区参与核心将培养一个充满活力和 通过促进以下讨论，在联盟内部和外部建立合作研究社区： 联合体会议和研讨会，支持向更广泛的领域传播联合体成果 研究和非专业社区，将选定的 NIH 职业发展获奖者整合到相关领域 联盟活动，以及让来自代表性不足群体的早期职业受训者接触肾脏- 重点关注结构性种族主义学术工作，以成功实施健康公平研究 和干预措施。多学科 RCC 团队将共同确保成功完成 针对肾脏健康差异的多项干预试验，并建立多样化和可持续的 由研究人员和社区合作伙伴组成的社区致力于改善肾脏健康 边缘化人群。

PROJECT ABSTRACT Recognizing the significant impact of structural racism on kidney health in minority populations, the NIH is creating a new Consortium focused on Interventions that Address Structural Racism to Reduce Kidney Health Disparities. The Consortium will bring together research teams from six Intervention Sites to conduct community-engaged intervention studies to address structural racism and reduce disparities across the spectrum of kidney health and disease. We propose to serve as the Research Coordinating Center (RCC) for the Consortium. The Duke RCC will leverage extensive institutional resources and expertise at Duke University to provide administrative leadership and research coordination to ensure seamless operations of the Consortium and successful conduct of Consortium studies; support rigorous data collection, data management, and data analysis for Consortium studies; and foster research collaboration, capacity-building, and workforce diversification in kidney health equity research. Three closely integrated cores will lead the core activities of the RCC. The Administrative and Coordination Core will provide administrative, operational, and logistical support to the Consortium, including coordinating meetings, developing a secure web-based communications and collaboration platform, supporting program management and regulatory submissions, administering an opportunity pool for ancillary studies, and continually evaluating and enhancing Consortium operations. The Data Management and Analysis Core will contribute to the final design of Consortium studies, provide data monitoring for multi-site Consortium studies, and support statistical analysis for multi-site Consortium studies and pooled analyses of common data elements across the Consortium. The Collaboration and Community Engagement Core will foster a vibrant and collaborative research community within and beyond the Consortium by facilitating discussion at Consortium meetings and workshops, supporting dissemination of Consortium results to the broader research and lay communities, integrating selected NIH career development awardees in relevant Consortium activities, and exposing early-career trainees from underrepresented groups to kidney- focused structural racism scholarly work in order to successfully implement health equity research and interventions. Together, the multidisciplinary RCC team will ensure the successful completion of multiple intervention trials targeting disparities in kidney health and build a diverse and sustainable community of researchers and community partners focused on improving kidney health in marginalized populations.