Microbial Restoriation in Crohn's Disease: A Randomised Trial of Faecal Microbial Transplanatation in Crohn's Disease
Microbial Restoriation in Crohn's Disease: A Randomised Trial of Faecal Microbial Transplanatation in Crohn's Disease
批准号:
nhmrc : 1195382
负责人:
金额:
$48.71万
依托单位国家:
澳大利亚
项目类别:
Investigator Grants
财政年份:
2021
资助国家:
澳大利亚
项目状态:
未结题
起止时间:
2021-01-01 至 2025-12-31
中文摘要
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英文摘要
Crohn's disease causes inflammation and damage to the digestive tract. Compelling evidence suggests that the bacteria in the gut play an important role in the onset of disease. Changing the gut bacteria through the administration of healthy stool to a patient, faecal microbiota transplantation (FMT), is safe and may be effective. This placebo controlled trial will determine whether FMT (delivered via capsule) can control inflammation in Crohn's. Results will change current treatment paradigms.
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