Membrane Transport Proteins Gordon Research Conference

描述（由申请人提供）：本申请申请为2008年和2010年戈登膜运输蛋白研究会议（GRC）提供部分支持。这是一个非常成功的GRC，重点关注最近发现的多种atp酶、离子通道和转运体。会议特别强调在通常不相互作用的研究人员之间发展科学和合作的联系，并将年轻的研究人员带入转运蛋白领域。2008年会议将是该小组的第六次会议，并将继续强调转运蛋白在其正常生理环境中的作用以及在各种疾病状态中的作用。该计划是完全国际化的，2008年的会议将有40名研究人员（25名来自美国，15名来自欧洲和日本），涵盖广泛的主题，包括：脑内葡萄糖转运，健康和疾病中的TRP通道，膜转运体的转运，多重耐药和抗微生物，抗癌和抗癫痫化合物，膜转运体结构，膜转运体的中枢神经系统疾病，重金属离子转运，膜转运和代谢传感，生物技术：分子传感器。在上次会议上决定每两年在美国和欧洲轮流举行一次会议，以使更多的研究人员，特别是研究生和博士后研究员能够在经济上获得会议的机会，从而强调了这次会议的国际范围。我们希望在每次会议上支持至少25名年轻的研究人员，并将积极寻求行业和私人基金会的支持，以进一步实现这一目标。特别强调选择妇女和少数民族发言者，并制定了招募少数民族参加者的计划。会议将遵循成熟的GRC形式，强调知名科学家之间以及知名科学家与年轻研究者之间的互动。这些膜转运蛋白会议的有效性将使用由GRC教师开发的完善的问卷进行评估。过去的五次会议都获得了高分；在2006年的会议上，超过90%的与会者将其评为“他们当年参加过的最好的会议”，并表示会议的演讲在“科学前沿”上“发人深省、令人振奋、令人兴奋”。2008年会议的地点是意大利的乔科，靠近交通便利的卢卡（25英里）、比萨（39英里）和佛罗伦萨（74英里）。该基地拥有现代化的设施，非常适合小型GRC风格的会议。提供了足够的空间，以便张贴多日的海报，从而进一步促进年轻和成熟的调查人员之间的互动。根据轮流举行会议的决定，2010年会议的地点暂定在缅因州的新英格兰大学。

DESCRIPTION (provided by applicant): This application requests partial support for the 2008 and 2010 Gordon Research Conferences (GRC) on Membrane Transport Proteins. This is a highly successful GRC that focuses on recent discoveries in a diverse group of ATPases, ion channels and transporters. The Conference places particular emphasis on developing connections, both scientific and collaborative, between investigators who do not normally interact and on bringing young investigators into the transport protein field. The 2008 Conference will be the 6th meeting of this group and will continue to stress the role of transport proteins in both their normal physiologic setting and their role(s) in a wide variety of disease states. The program is fully international, the 2008 meeting will feature 40 investigators (25 from the USA, 15 from Europe and Japan) covering a wide range of topics including: Glucose Transport in the Brain, TRP Channels in Health and Disease, Trafficking of Membrane Transporters, Multiple Drug Resistance and Anti-microbial, Anti-cancer and Antiepileptic Compounds, Structure of Membrane Transporters, CNS Diseases of Membrane Transporters, Heavy Metal Ion Transport, Membrane Transport and Metabolic Sensing, and Biotechnology: Molecular Sensors. The international scope of this conference is emphasized by the decision at the last meeting to alternate every two years between venues in the US and Europe in an effort to make the conference financially accessible to more investigators, particularly graduate students and post doctoral fellows. We expect to support a minimum of 25 young investigators at each meeting and will actively seek support from both industry and private foundations to further this goal. Particular emphasis has been placed on selecting both women and minority speakers and a plan is in place to recruit minority participants. The meetings will adhere to the well developed GRC format which emphasizes interaction between established scientists and between established scientists and young investigators. The effectiveness of these Membrane Transport Protein conferences will be evaluated using the well established questionnaires developed by the GRC faculty. The past five conferences have rated high marks; greater than 90% of the participants in the 2006 conference rated it as the "best conference they attended that year" and indicated the presentations were 'thought provoking, stimulating and exciting' at the 'frontiers of science'. The venue for the 2008 Conference is Il Ciocco, Italy close to convenient transportation sites, Lucca (25 miles), Pisa (39 miles) and Florence (74 miles). The site has modern facilities ideally suited to small GRC style meetings. Sufficient space is provided to have posters available for multiple days thus further facilitating interactions between younger and established investigators. In keeping with the decision to alternate meetings, the venue for the 2010 conference is tentatively planned to be at the University of New England in Maine.