ETHNIC VARIATIONS IN ANTIDEPRESSANT RESPONSE

抗抑郁药反应的种族差异

• 批准号: 7606150
• 负责人: IRA Marc LESSER
• 金额: $ 1.4万
• 依托单位: LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7606150
• 关键词: Affect; African American; Antidepressive Agents; Caucasians; Caucasoid Race; Celexa; Computer Retrieval of Information on Scientific Projects Database; Depressed mood; Funding; Genes; Grant; Institution; Mental Depression; Moods; Patients; Persons; Pharmaceutical Preparations; Research; Research Personnel; Resources; Source; Therapeutic; United States Food and Drug Administration; United States National Institutes of Health; Variant; genetic profiling; improved; response; socioeconomics

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To determine how the genetic profile of African American and Caucasian depressed patients influence their responses to the study medication celexa. Celexa is a medication that is known to help improve a person's mood and has been approved by the FDA to use in the treatment of depression. This study will also examine the influence of socioeconomic variables in determining the course and treatment response and the influence of other genes that may also affect the therapeutic response of these two groups to the antidepressant celexa

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 确定非裔美国人和白人抑郁症患者的遗传特征如何影响他们对研究药物 celexa 的反应。 Celexa 是一种已知有助于改善人情绪的药物，并已被 FDA 批准用于治疗抑郁症。这项研究还将研究社会经济变量在确定病程和治疗反应方面的影响，以及其他基因的影响，这些基因也可能影响这两组患者对抗抑郁药 celexa 的治疗反应。