COMPARISON OF DIFFERENT COMBINATION CHEMOTHERAPY REGIMENS IN CHILDREN WITH ALL

儿童不同联合化疗方案与所有患者的比较

• 批准号: 7607499
• 负责人: YOUSIF H MATLOUB
• 金额: $ 0.24万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607499
• 关键词: Acute; Chemotherapy-Oncologic Procedure; Child; Childhood Acute Lymphocytic Leukemia; Clinical Trials; Combination Chemotherapy; Computer Retrieval of Information on Scientific Projects Database; Databases; Drug usage; Evaluation; Funding; Grant; Institution; National Cancer Institute; Patients; Pharmaceutical Preparations; Phase III Clinical Trials; Physician Data Query; Radiation therapy; Randomized; Recruitment Activity; Research; Research Personnel; Resources; Source; Standards of Weights and Measures; Treatment Protocols; United States National Institutes of Health; Week; Work; cancer cell; chemotherapy; follow-up; killings

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is no longer recruiting patients. (Clinical trial summary from the National Cancer Institute's PDQ¿ database) Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Giving more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating childhood acute lymphoblastic leukemia. This randomized Phase III trial is comparing different combination chemotherapy regimens to see how well they work in treating children with acute lymphoblastic leukemia.Patients will receive standard combination chemotherapy for 8 weeks. Patients will then be randomly assigned to one of four regimens for additional chemotherapy. Treatment may continue for up to 3 years. Some patients may also undergo radiation therapy. Patients will receive follow-up evaluations every 4-8 weeks for 1 year, every 3 months for 1 year, every 6 months for 1 year, and once a year thereafter.

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