REGULATION OF VITAMIN D METABOLISM

维生素 D 代谢的调节

• 批准号: 7607137
• 负责人: NORMAN H BELL
• 金额: $ 0.96万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607137
• 关键词: Characteristics; Color; Computer Retrieval of Information on Scientific Projects Database; Daily; Exposure to; Funding; Grant; Individual; Institution; Malignant neoplasm of prostate; Melanins; Metabolism; Osteoporosis; Participant; Pigments; Production; Purpose; Recruitment Activity; Regulation; Research; Research Personnel; Resources; Risk; Skin; Source; Sunlight; United States National Institutes of Health; Vitamin D; Vitamin D Deficiency; Vitamins; skin color

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to determine whether the daily requirement of vitamin D is different in individuals with different skin color. Vitamin D is obtained either from dietary sources or is produced in the skin by exposure to sunlight. However, in dark-skinned individuals, production is reduced by increased amounts of melanin, which is the pigment that gives the skin its characteristic color. The reduced vitamin D production, in some individuals, could result in vitamin D deficiency. Vitamin D deficiency may increase the risk for developing osteoporosis or prostate cancer. One hundred participants will be recruited for this study.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是确定不同肤色的个体对维生素D的每日需求量是否不同。 维生素D可以从饮食中获得，也可以通过暴露在阳光下在皮肤中产生。 然而，在黑皮肤的个体中，黑色素的产生会因黑色素的增加而减少，黑色素是赋予皮肤特征颜色的色素。 在某些个体中，维生素D产量减少可能导致维生素D缺乏症。 维生素D缺乏可能会增加患骨质疏松症或前列腺癌的风险。 本研究将招募100名受试者。