EVENT-RELATED POTENTIALS IN SCHIZOPHRENIA DURING VISUAL SEARCH

视觉搜索期间精神分裂症患者的事件相关电位

• 批准号: 7608134
• 负责人: James M. Gold
• 金额: $ 2.07万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2008-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7608134
• 关键词: Attention; Computer Retrieval of Information on Scientific Projects Database; Contralateral; Event-Related Potentials; Funding; Grant; Impaired cognition; Impairment; Institution; Operative Surgical Procedures; Patients; Process; Rate; Research; Research Personnel; Resources; Schizophrenia; Source; System; Time; United States National Institutes of Health; research study; visual search

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Event-Related Potentials in Schizophrenia During Visual Search. Cognitive impairment is a central feature of schizophrenia. We plan to assess impairments in the operation of attention within perceptual systems in schizophrenia (SC). Current research in our lab suggests that patients with SC have slower visual search rates, but it is not clear whether this slowness is a consequence of slowed perceptual processes or specific impairments in attention. That is, if the patients' perceptual systems simply require more time to determine if a given item is a target or a nontarget, then their search rates will be slowed. To assess the attentional component of the visual search process, this experiment will use ERP recordings, focusing on an attention-related component called "N2pc" (for N2-posterior-contralateral).

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 精神分裂症患者视觉搜索过程中的事件相关电位认知障碍是精神分裂症的一个主要特征。我们计划评估精神分裂症(SC)患者知觉系统内注意力操作的障碍。我们实验室目前的研究表明，SC患者的视觉搜索速度较慢，但尚不清楚这种缓慢是知觉过程缓慢的结果，还是特定的注意力障碍的结果。也就是说，如果患者的感知系统只是需要更多的时间来确定给定的物品是目标还是非目标，那么他们的搜索速度将会减慢。为了评估视觉搜索过程中的注意力成分，本实验将使用事件相关电位记录，重点关注与注意力相关的成分N2pc(代表n2-后方-对侧)。