BORONATED TUMOR SEEKING PORPHYRINS SYNTHESIS & TESTING

硼化肿瘤寻找卟啉的合成

• 批准号: 7601800
• 负责人: STEPHEN B KAHL
• 金额: $ 0.45万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7601800
• 关键词: Animals; Boron Neutron Capture Therapy; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Malignant Neoplasms; Mass Spectrum Analysis; Porphyrins; Research; Research Personnel; Resources; Source; Testing; United States National Institutes of Health; design; tumor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project focuses on the design and synthesis of boronated porphyrins and other molecules for boron neutron capture therapy of cancer. These compounds will subsequently be tested in small animals. Since this is predominantly a synthetic organic project, mass spectrometry is an extremely important aspect of the project for use in characterizing the compounds.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本项目主要致力于硼化卟啉及其他用于硼中子俘获治疗癌症的分子的设计与合成。这些化合物随后将在小动物中进行测试。由于这主要是一个合成有机项目，质谱法是该项目用于表征化合物的一个极其重要的方面。