EFFECT OF SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRI) ON SEX HORMONE LEVELS

选择性血清素再摄取抑制剂 (SSRI) 对性激素水平的影响

• 批准号: 7604205
• 负责人: BARBARA D BARTLIK
• 金额: $ 0.01万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7604205
• 关键词: Androstenedione; Computer Retrieval of Information on Scientific Projects Database; Estradiol; Funding; Gonadal Steroid Hormones; Grant; Institution; Pregnenolone; Prolactin; Research; Research Personnel; Resources; Selective Serotonin Reuptake Inhibitor; Source; Stanolone; Testosterone; United States National Institutes of Health; treatment effect

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To determine the effect of treatment with SSRIs on levels of precursors, 17-oh pregnenolone androstenedione, DHEAS, DHT, total testosterone, free testosterone, prolactin and estradiol. We hypothesize that all of these except for prolactin will be decreased with SSRI treatment, and prolactin will be increased.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 确定SSRIs治疗对前体、17-羟基异烯醇酮雄烯二酮、DHEAS、DHT、总睾酮、游离睾酮、催乳素和雌二醇水平的影响。 我们推测，SSRI治疗后，除催乳素外，所有这些激素都会降低，而催乳素会升高。