Using Multimedia Technologies to Disseminate an HIV Prevention Intervention

描述（由申请人提供）：尽管20年来的研究证明了基于科学的干预措施在减少风险行为方面的有效性，但艾滋病毒预防传播的科学仍处于早期阶段。艾滋病毒感染在世界范围内继续上升，异性接触仍然是主要和不断升级的传播途径。迫切需要提高艾滋病毒预防干预传播方法的能力、规模和速度，例如在教育和医疗领域日益实施的那些方法，这些方法使用多媒体和基于互联网的方法。这项修订后的申请提出了一项技术转移研究，通过测试采用多媒体和基于互联网的技术来实施基于证据的夫妻一级艾滋病毒预防干预是否能改善现有传播策略之外的采用结果，从而推进艾滋病毒预防传播研究的科学。建议进行一项随机临床试验，以比较向纽约州社区组织（cbo）的客户传播传统的、手动的项目连接（传统）一揽子方案的有效性。项目连接（传统）是一项针对艾滋病毒/性传播感染高危异性伴侣的6期基于关系的艾滋病毒/性传播感染预防干预，与基于多媒体的、基于互联网的项目连接（多媒体）版本的有效性。80名提供艾滋病毒预防服务的参与社区组织将随机接受传统或多媒体干预和培训包。所有机构将在培训后的头两个月内接受为期两天的现场培训和由研究调查人员计划的两次技术援助电话会议。由每个机构最多6名工作人员（共480名参与者）完成的电话评估将在技术转让后的基线、6个月、12个月和18个月测量主要结果、中介、调节和处理测量变量。本研究的主要结果是采用了Connect干预措施。分析单位是CBO。这项拟议的研究将由Susan Witte博士、Nabila EI-Bassel博士和哥伦比亚大学社会工作学院社会干预小组的调查小组进行，并与艾滋病行为研究中心的Robert Remien博士和哥伦比亚新媒体教学和学习中心（CCNMTL）的执行主任Frank Moretti博士合作。

DESCRIPTION (provided by applicant): Despite two decades of research demonstrating the efficacy of science-based interventions to reduce risk behaviors, the science of HIV prevention dissemination is still in its early stages. HIV infections continue to rise worldwide, and heterosexual contact remains the primary and escalating route of transmission. There is a critical need for increased capacity, scale and speed for HIV prevention intervention dissemination approaches, such as those increasingly implemented in educational and medical arenas, which use multimedia and internet-based approaches. This revised application proposes a technology transfer study that will advance the science of HIV prevention dissemination research by testing whether employing multimedia and internet-based technology for implementation of an evidence-based, couple-level HIV prevention intervention improves adoption outcomes beyond existing dissemination strategies. Proposed is a randomized clinical trial to compare the effectiveness of disseminating a traditional, manualized package of Project Connect (Traditional), a 6-session, relationship-based HIV/STI prevention intervention for heterosexual couples at high risk for HIV/STI transmission, versus a multimedia, internet-based version of Project Connect (Multimedia) to clients at community-based organizations (CBOs) across New York State. Eighty participating CBOs providing HIV prevention services will be randomized to receive either the Traditional or Multimedia intervention and training packages. All agencies will receive two days of on-site training and two planned technical assistance conference calls by study investigative staff in the first two months following training. Telephone assessments completed by up to 6 staff at each agency (total of 480 participants) will measure primary outcomes, mediating, moderating and process measure variables at baseline, 6-, 12- and 18-months post-technology transfer. The primary outcome of the study is adoptions of the Connect intervention. The unit of analysis is the CBO. The proposed study will be conducted by Dr. Susan Witte, Dr. Nabila EI-Bassel, and the investigative team at the Social Intervention Group at the Columbia University School of Social Work, in collaboration with Dr. Robert Remien, of the HIV Center for Behavioral Research and Dr. Frank Moretti, Executive Director of the Columbia Center for New Media Teaching and Learning (CCNMTL).