CORE--Gene Expression
CORE--Gene Expression
批准号:
7329976
负责人:
SHELDON I FEINSTEIN
金额:
$11.96万
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-07-01 至 2012-06-30
关键词:
Adenovirus VectorAnimalsCellsConsultationsDoctor of PhilosophyEscherichia coliEukaryotic CellGene ExpressionGenesGenotypeGoalsIn VitroInsectaKnock-in MouseKnock-outMammalian CellMetabolismMolecular BiologyMolecular Biology TechniquesNamesParticipantPichiaPolymerase Chain ReactionPositioning AttributePreparationPrincipal InvestigatorProteinsPurposeRecombinant ProteinsResearchResearch PersonnelRoleServicesSite-Directed MutagenesisSmall Interfering RNASystemTimeTitleTransfectionTransgenic MiceYeastsabstractinginstrumentinterestprogramsprotein expressionsurfactant
中文摘要
主要研究者:Fisher Aron B。
a.核心单位名称
核心A:基因表达
名称eraCommons在项目中的作用
谢尔顿岛Feinstein博士范斯坦的核心主任宾夕法尼亚大学高级研究投资。
摘要:
基因表达核心,核心A的目的是促进基因和基因产物的研究
这些都是项目感兴趣的。本申请中的所有拟议项目都将研究
表面活性物质代谢在体外、细胞和动物中研究这些蛋白质的能力将是研究这些蛋白质的关键。
项目该核心将为所有项目提供服务、工具、专门知识和援助,
实现这些目标。具体来说,核心将在E.大肠杆菌、昆虫细胞和
酵母毕赤酵母(Pichia pastoris)
英文摘要
Principal Investigator: Fisher Aron B.
a. TITLE OF CORE UNIT
CORE A: GENE EXPRESSION
Name eraCommons Role on Project Affiliation Position
Sheldon I. Feinstein, Ph.D. feinsteins Core Director Univ. Penn Sr. Research Invest.
ABSTRACT:
The purpose of the Gene Expression Core, Core A is to facilitate the study of the genes and gene products
that are of interest to the projects. All of the proposed projects in this application will examine key proteins in
surfactant metabolism. The ability to study these proteins in vitro, in cells and in animals will be critical to the
projects. The Core will provide services, instruments, expertise and assistance to all the projects in
accomplishing these goals. Specifically, the Core will generate recombinant proteins in E. coli, insect cells and
the yeast, Pichia pastoris, perform
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会议论文
Evaluation of a peptide that inhibits the activation of NOX2 and the generation of reactive oxygen species in protection against acute lung injury
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批准号:9908865
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项目类别:
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资助金额:$29.99万
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财政年份:2020
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负责人:SHELDON I FEINSTEIN
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依托单位:
CORE--Molecular Engineering and Protein Preparation
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批准号:7796694
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项目类别:
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资助金额:$35.67万
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财政年份:2009
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负责人:SHELDON I FEINSTEIN
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依托单位:
CORE--Molecular Engineering and Protein Preparation
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批准号:6968189
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项目类别:
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资助金额:$21.05万
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财政年份:2004
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负责人:SHELDON I FEINSTEIN
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依托单位:
Core--Gene expression
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批准号:6569894
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项目类别:
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资助金额:$24.07万
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财政年份:2001
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负责人:SHELDON I FEINSTEIN
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依托单位:
ROLE OF A TRANSCRIPTION FACTOR FAMILY IN LUNG DEVELOPMENT
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批准号:6358068
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项目类别:
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资助金额:$21.19万
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财政年份:2000
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负责人:SHELDON I FEINSTEIN
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依托单位:
ROLE OF A TRANSCRIPTION FACTOR FAMILY IN LUNG DEVELOPMENT
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批准号:6202518
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项目类别:
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资助金额:$21.19万
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财政年份:1999
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负责人:SHELDON I FEINSTEIN
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依托单位:
ROLE OF A TRANSCRIPTION FACTOR FAMILY IN LUNG DEVELOPMENT
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批准号:6110706
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项目类别:
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资助金额:$21.19万
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财政年份:1998
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负责人:SHELDON I FEINSTEIN
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依托单位:
ROLE OF A TRANSCRIPTION FACTOR FAMILY IN LUNG DEVELOPMENT
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批准号:6242700
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项目类别:
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资助金额:$20.12万
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财政年份:1997
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负责人:SHELDON I FEINSTEIN
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依托单位:
C/EBP AND ALVEOLAR TYPE II CELL DIFFERENTIATION
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批准号:2029281
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项目类别:
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资助金额:$22.03万
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财政年份:1996
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负责人:SHELDON I FEINSTEIN
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依托单位:
C/EBP AND ALVEOLAR TYPE II CELL DIFFERENTIATION
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批准号:2839012
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项目类别:
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资助金额:$23.38万
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财政年份:1996
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负责人:SHELDON I FEINSTEIN
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依托单位:
C/EBP AND ALVEOLAR TYPE II CELL DIFFERENTIATION
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批准号:2609348
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项目类别:
-
资助金额:$22.69万
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财政年份:1996
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负责人:SHELDON I FEINSTEIN
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依托单位:
C/EBP AND ALVEOLAR TYPE II CELL DIFFERENTIATION
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批准号:6125927
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项目类别:
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资助金额:$24.08万
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财政年份:1996
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负责人:SHELDON I FEINSTEIN
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依托单位:
CORE--Molecular Engineering and Protein Preparation
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批准号:7624185
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项目类别:
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资助金额:$19.59万
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财政年份:--
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负责人:SHELDON I FEINSTEIN
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依托单位:
ROLE OF A TRANSCRIPTION FACTOR FAMILY IN LUNG DEVELOPMENT
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批准号:5214467
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:SHELDON I FEINSTEIN
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依托单位:--
CORE--Molecular Engineering and Protein Preparation
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批准号:7312638
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项目类别:
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资助金额:$20.34万
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财政年份:--
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负责人:SHELDON I FEINSTEIN
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依托单位:
CORE--Molecular Engineering and Protein Preparation
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批准号:7418359
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项目类别:
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资助金额:$21.99万
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财政年份:--
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负责人:SHELDON I FEINSTEIN
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依托单位:
Core--Gene expression
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批准号:6994412
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项目类别:
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资助金额:$26.0万
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财政年份:--
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负责人:SHELDON I FEINSTEIN
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依托单位:
REGULATION OF SURFACTANT PROTEIN GENE EXPRESSION
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批准号:5213271
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:SHELDON I FEINSTEIN
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依托单位:--
CORE--Gene Expression
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批准号:8112421
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项目类别:
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资助金额:$11.49万
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财政年份:--
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负责人:SHELDON I FEINSTEIN
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依托单位:
CORE--Gene Expression
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批准号:8306067
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项目类别:
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资助金额:$11.49万
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财政年份:--
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负责人:SHELDON I FEINSTEIN
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依托单位:
海外基金