CORE--Gene Expression

首席研究员：Fisher Aron B. a.核心单位名称 核心 A：基因表达 名称eraCommons 在项目隶属关系中的角色职位 谢尔登·范斯坦博士范斯坦斯大学核心主任佩恩高级研究投资。 摘要： 基因表达核心 Core A 的目的是促进基因和基因产物的研究 是项目感兴趣的。本申请中提出的所有项目都将检查以下物质中的关键蛋白质： 表面活性剂代谢。在体外、细胞和动物中研究这些蛋白质的能力对于 项目。该核心将为所有项目提供服务、工具、专业知识和援助 实现这些目标。具体来说，核心将在大肠杆菌、昆虫细胞和 酵母，毕赤酵母，执行

Principal Investigator: Fisher Aron B. a. TITLE OF CORE UNIT CORE A: GENE EXPRESSION Name eraCommons Role on Project Affiliation Position Sheldon I. Feinstein, Ph.D. feinsteins Core Director Univ. Penn Sr. Research Invest. ABSTRACT: The purpose of the Gene Expression Core, Core A is to facilitate the study of the genes and gene products that are of interest to the projects. All of the proposed projects in this application will examine key proteins in surfactant metabolism. The ability to study these proteins in vitro, in cells and in animals will be critical to the projects. The Core will provide services, instruments, expertise and assistance to all the projects in accomplishing these goals. Specifically, the Core will generate recombinant proteins in E. coli, insect cells and the yeast, Pichia pastoris, perform