COBRE: UID: BIOINFORMATICS CORE FACILITY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该项目实施了生物信息学核心设施，提供硬件、软件、教育/培训能力和人员配备，使生物医学研究人员能够分析生物数据并对其进行建模。这一核心由科布雷与爱达荷州布林和INBRE计划(P20RR16454)等其他来源共同资助。去年，在Cobre资金的支持下，我们增加了可用的磁盘存储空间，以适应呈指数级增长的数据库。利用其他资金，我们还建造了一台新的高性能(位，16节点XServe)集群计算机，作为探索未来集群体系结构的测试平台，并在软件端增加了第三台(更强大的)Sun V880服务器，我们升级了核心生物信息学软件，用于研究和培训，并增强了我们的数学和分子建模能力。我们还将生物信息学和计算生物学(BCB)的硕士/博士课程扩大到17名博士生和3名硕士研究生。大多数学生都在与科布雷的教职员工一起进行研究项目。我们还开设了正式课程，参加了第三届年度Brin生物信息学研讨会，并在9月份主办了Cobre海报会议。这一核心的工作人员现在包括：主任詹姆斯·A·福斯特、系统管理员肯·布莱尔、生物信息学协调员塞莱斯特·布朗、四名学生助理系统管理员和两名学生程序员。我们今年的计划是：改进生产集群计算机以提高可用性和可靠性，招聘第二名全职系统管理员负责集群计算，并续签软件许可证。我们还在协助NIH Lariat项目，这是一个Brin补充项目，旨在加强电信，以支持我们地区IDEA国家之间的合作生物医学研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project implements a bioinformatics core facility, which provides hardware, software, educational/training capabilities, and staffing that enable biomedical researchers to analyze and model biological data. This core is funded by COBRE in conjunction with other sources such as the Idaho BRIN and INBRE Programs (P20RR16454). In the last year, with COBRE funds, we have increased the available disk storage, in order to accommodate exponentially increasing databases. Using other funds, we have also built a new high performance (64-bit, 16 node Xserve) cluster computer, as a test platform for exploring future cluster architectures, and added a third (more powerful) Sun V880 server On the software side, we have upgraded our core bioinformatics software for both research and training, and have augmented our mathematical and molecular modeling capabilities. We have also expanded our MS/PhD program in Bioinformatics and Computational Biology (BCB) to 17 doctoral students and 3 MS students. Most students are working on research projects with COBRE faculty. We also offered formal courses, participated in the third annual BRIN Bioinformatics Workshop, and hosted a COBRE poster session in September. Staff in this core now include: James A. Foster, Director; Ken Blair, Systems Administrator; Celeste Brown, Bioinformatics Coordinator; four student assistant systems administrators; and two student programmers. Our plans for this year are: to improve the production cluster computer to improve availability and reliability, to recruit a second, full-time systems administrator for cluster computing, and to renew software licenses. We are also assisting with the NIH Lariat project, a BRIN supplement to enhance telecommunications in support of collaborative biomedical research among IDEA states in our region.