Research Training Program in Environmental Pediatrics

描述（由申请人提供）：今天的儿童面临多种环境危害的风险-有毒化学品，社会压力源和建筑环境的危害。越来越多的证据表明，环境中的暴露有助于引起许多常见的儿科疾病，而且还可能增加成人生活中的疾病风险。然而，尽管环境对人类健康具有潜在的重要性，但很少有儿科医生接受过研究、诊断、治疗或预防由环境引起的疾病的培训，也很少有学术健康中心开设环境儿科项目或接受过指导此类项目的研究领导。IOM指出，国家需要扩大环境医学领域的科研队伍。为了培养下一代环境儿科的医师研究人员和学术领袖，西奈山医学院（Mount Sinai School of Medicine）寻求支持，针对临床训练有素的儿科医生，开展为期3年的住院医师后跨学科研究培训计划。环境儿科流行病学研究将是核心培训主题。主要关注的疾病将是神经发育障碍；糖尿病和肥胖症；还有哮喘和过敏。我们打算为我们的研究员提供一个强大的方法论基础，并为他们配备一套多功能的工具，他们可以应用于研究环境儿科学的广泛科学问题。研究员的选择将是竞争性的，重点将放在招募代表性不足的少数民族。在第一年，研究员将接受流行病学、生物统计学、环境医学、研究设计和研究方法方面的教学培训。一个分子流行病学系列研讨会和一门基金写作课程将作为核心课程的补充。在第二年和第三年，重点将放在一个指导的研究项目。研究员将在儿科环境卫生专科单位获得环境儿科的临床经验。一位导师和1-2名其他教员将指导每位研究员。每位学员的进步将每半年评估一次。预期成果包括：原创论文至少1-2篇；撰写至少2- 3张海报和/或摘要，在区域或国家会议上展示；成功完成环境卫生硕士学位；在K08或R01拨款建议的第三年进行发展；以及向独立调查员身份转变的证据。一个执行教员委员会和一个外部咨询委员会已经成立，以指导该计划。该项目建立在西奈山儿科环境健康奖学金的基础上，该奖学金自2002年以来一直由门诊儿科协会提供支持。它与儿童环境健康和疾病预防研究中心相连；儿童环境卫生专科单位；以及最近成立的全国儿童研究先锋中心。

DESCRIPTION (provided by applicant): Children today are at risk of exposure to multiple environmental hazards - toxic chemicals, social stressors and the hazards of the built environment. Evidence is mounting that exposures in the environment contribute to causation of many common pediatric diseases, and also that they may increase risk for disease in adult life. Yet despite the potential importance of the environment to human health, few pediatricians are trained to study, diagnose, treat or prevent disease of environmental origin, and few academic health centers have programs in environmental pediatrics or research leaders trained to direct such programs. The IOM states that there is national need to expand the scientific workforce in environmental medicine. To train the next generation of physician-researchers and academic leaders in environmental pediatrics, the Mount Sinai School of Medicine seeks support for a 3-year, post-residency interdisciplinary research training program targeted to clinically trained pediatricians. Epidemiological research in environmental pediatrics will be the core training theme. Diseases of principal focus will be neurodevelopmental disorders; diabetes and obesity; and asthma and allergy. We intend to provide our fellows with a robust methodological base and to equip them with a versatile set of tools that they can apply to study a wide range of scientific questions in environmental pediatrics. Selection of fellows will be competitive, and emphasis will be placed on recruitment of underrepresented minorities. In year 1, fellows will receive didactic training in epidemiology, biostatistics, environmental medicine, study design and research methodology. A seminar series in molecular epidemiology and a course on grant writing will complement the core curriculum. In years 2 and 3, emphasis will be placed on a mentored research project. Fellows will gain clinical experience in environmental pediatrics in the Pediatric Environmental Health Specialty Unit. A mentor and 1-2 additional faculty members will guide each fellow. Each fellow's progress will be evaluated semi-annually. Expected outcomes include: authorship of at least 1-2 manuscripts based on original research; authorship of at least 2- 3 posters and/or abstracts for presentation at regional or national meetings; successful completion of an MPH degree focusing on environmental health; development in year 3 of a K08 or R01 grant proposal; and evidence of transition toward independent investigator status. An Executive Faculty Committee and an External Advisory Board have been established to guide the program. This program builds on a fellowship in Pediatric Environmental Health supported at Mount Sinai since 2002 by the Ambulatory Pediatric Association. It links to a Center for Children's Environmental Health and Disease Prevention Research; a Pediatric Environmental Health Specialty Unit; and a recently established Vanguard Center for the National Children's Study.