Functional characterization of a new S6 kinase-1 isoform

新 S6 激酶 1 亚型的功能表征

• 批准号: 7471032
• 负责人: SHEILA COLLINS
• 金额: $ 25.2万
• 依托单位: THE HAMNER INSTITUTES
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7471032
• 关键词: 1-Phosphatidylinositol 3-Kinase; Abdomen; Adipocytes; Adipose tissue; Adult; Age; Animals; Aspartic Acid; Assimilations; Binding; Biological; Body Size; Brown Fat; Canis familiaris; Catalysis; Catalytic Domain; Cell Line; Cell model; Chronic; Complex; Coupled; Decision Making; Development; Diabetes Mellitus; Diet; Dimensions; Disruption; Docking; Elements; Enzymes; Exhibits; Expenditure; Exploratory/Developmental Grant; Fatty acid glycerol esters; Feedback; Felis catus; Foundations; Gene Expression; Genes; Glycine; Growth; Heart Diseases; Heating; Housing; Human; Immune Sera; Insulin; Insulin Receptor; Insulin-Like Growth Factor I; Intake; Knockout Mice; Length; Life; Lysine; Maintenance; Malignant Neoplasms; Mammals; Metabolic Diseases; Metabolism; Mitochondria; Monkeys; Mus; N-terminal; Nature; Newborn Infant; Nuclear; Numbers; Nutrient; Obesity; Organ; Pathway interactions; Pattern; Phosphorylation; Phosphotransferases; Play; Principal Investigator; Process; Protein Isoforms; Proteins; Public Health; Purpose; RNA Splicing; Radiology Specialty; Rattus; Receptor Signaling; Regulation; Research Personnel; Resistance; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinase; Role; ST5 Protein; ST5 gene; Signal Pathway; Signal Transduction; Signal Transduction Pathway; Sirolimus; Site; Stretching; System; Temperature; Testing; Thermogenesis; Tissue Expansion; Tissue Sample; Transcript; Variant; adipocyte differentiation; cell type; day; fatty acid oxidation; genetic manipulation; human tissue; inhibitor/antagonist; insight; interest; lipid biosynthesis; loss of function; member; novel; prevent; programs; receptor; research study; ribosomal protein S6 kinase 1; tool