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中文摘要
翻译
药物遗传学、药效学和药代动力学分析实验室的使命 (3P)通过提供准确和高效的最新数据和技术来推动临床癌症研究 药物遗传学、药效学和药代动力学参数分析。 3P实验室为癌症中心成员提供三项服务:仪器、分析 服务和样品采集服务。 1.仪器设备 3P实验室负责维护和指导癌症中心成员使用所有实验室设备 安置在3P实验室。3P实验室有1200平方英尺的实验室空间和240平方英尺的空间 拥有超过25台实验室仪器的办公空间。这个空间是专门为 有效使用和维护分析仪器。实验室的设计还有助于及时和 有效地处理临床样本。 2.分析服务 3P实验室旨在开发和执行各种生物分析工具 方法,包括处理和分析PK/PD/PG研究的样本,以支持第一、第二、第三和第三阶段 化学预防临床试验。这项服务包括开发和执行原始化验 新的试剂,监测内源性生物化学物质的分析,基因分型和突变分析以及 适用的现有分析方法。 3.样本采集服务(SAS) 3P实验室还为UWCCC的所有临床试验提供样本采集服务。这项服务是 提供给所有参与需要获取、处理、存储和运输的临床试验的研究人员 用于PK/Pd/PG研究的样本。
英文摘要
The mission of the Analytical Laboratory for Pharmacogenetics, Pharmacodynamics and Pharmacokinetics (3P) is to advance clinical cancer research by providing accurate and efficient state of the art data and analyses of pharmacogenetics, pharmacodynamics and pharmacokinetics parameters. The 3P Laboratory has three services available to Cancer Center members, instrumentation, analytical service and the sample acquisition service. 1. Instrumentation The 3P Laboratory maintains and instructs Cancer Center members on the use of all laboratory equipment housed in the 3P Laboratory. The 3P Laboratory has 1,200 square feet of laboratory space and 240 square feet of office space which house over 25 laboratory instruments. The space was specially designed for efficient use and maintenance of analytical instruments. The laboratory design also facilitates timely and efficient processing of clinical samples. 2. Analytical Services The 3P Laboratory is designed as a facility for developing and executing a wide variety of bioanalytical methods, including processing and analyzing samples for PK/PD/PG studies in support of Phase I, II, III and chemoprevention clinical trials. This service includes development and performance of original assays for new agents, assays to monitor endogenous biochemicals, genotyping and mutation assays and adaptation of existing methodology for analyses where applicable. 3. Sample Acquisition Services (SAS) The 3P Laboratory also offers a Sample Acquisition Service for all UWCCC clinical trials. This service is offered to all investigators participating in clinical trials requiring acquisition, processing, storage and shipping of samples for PK/PD/PG studies.
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Combating melanoma resistance by targeting ABL1/2
  • 批准号:
    10444295
  • 项目类别:
  • 资助金额:
    $63.48万
  • 财政年份:
    2022
  • 负责人:
    JILL MARIE KOLESAR
  • 依托单位:
Combating melanoma resistance by targeting ABL1/2
  • 批准号:
    10626076
  • 项目类别:
  • 资助金额:
    $57.15万
  • 财政年份:
    2022
  • 负责人:
    JILL MARIE KOLESAR
  • 依托单位:
Drug Discovery, Delivery, and Translational Therapeutics Research Program
  • 批准号:
    10204892
  • 项目类别:
  • 资助金额:
    $3.2万
  • 财政年份:
    2013
  • 负责人:
    JILL MARIE KOLESAR
  • 依托单位:
Drug Discovery, Delivery, and Translational Therapeutics Research Program
  • 批准号:
    10470112
  • 项目类别:
  • 资助金额:
    $3.2万
  • 财政年份:
    2013
  • 负责人:
    JILL MARIE KOLESAR
  • 依托单位:
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