Interdisciplinary studies in hormone function

描述（由申请人提供）： 马萨诸塞州大学医学院内分泌学培训计划的总体目标在过去的30年里一直是NRSA的目标，即“.准备合格的个人的职业生涯，显着影响国家的研究议程。“该计划的具体目标是培养临床（医学博士）基础（Ph.D.）科学家，其研究和/或学术病人护理事业将改善内分泌疾病和糖尿病的护理和结果。在过去的30年里，我们的大多数学员都进入了学术研究，政府和行业的竞争性职业。 该计划提供经典的内分泌学和糖尿病研究机会，但此外还寻求扩大所提供培训的广度，以涵盖临床/转化性质的尖端概念、技术和项目。马萨诸塞州大学医学院经历了设施和研究机会的重大扩张。新的计划功能利用机构的增长，该计划为有才华，训练有素，积极的博士后学员提供了丰富的研究经验。强调四个领域：糖尿病和胰岛移植免疫学、神经内分泌学、细胞信号传导和骨与性腺发育研究。所有领域都处于内分泌研究国家优先事项的前列。 我们再次建议支持3 MD。3 PhD学员每年2-3年。所有受训人员在整个研究金期间都将得到个别辅导。一个正式的指导委员会将继续监测每个受训人员的进展情况。一项吸引本科医学生直接参加该项目的招聘计划将继续下去，并允许在住院期间开始研究。M.D.学员将有机会获得研究生院的分子和细胞生物学课程和博士学位。学员将参加特别研讨会，以提高他们将基础研究转化为临床的知识。项目教师由18名科学家组成的精干“核心”，每个人都是某个重点领域的校外资助权威。我们相信，拟议的组织和教育计划将继续提高我们的学员的研究经验，并解决国家对医学和研究需要这些重要领域的忠诚调查人员和学者的需求。

DESCRIPTION (provided by applicant): The overall objective of the Endocrinology Training Program at the University of Massachusetts Medical School for the past 30 year has been that of the NRSA, namely "...to prepare qualified individuals for careers that significantly impact the Nation's research agenda." The Program's specific goal is to train both clinical (M.D.) and basic (Ph.D.) scientists whose research and/or academic patient care careers will improve the care and outcome of endocrine diseases and diabetes mellitus. The majority of our trainees have entered competitive careers in academic research, government, and industry during the past 30 years. The Program offers classical endocrinology and diabetes research opportunities, but in addition seeks to extend the breadth of the training offered to encompass cutting edge concepts, technologies, and programs that are clinical/translational in nature. The University of Massachusetts Medical School has undergone major expansion of facilities and research opportunities. New Program features capitalize on institutional growth, and the Program provides a rich research experience for talented, well-trained, and motivated postdoctoral trainees. Four areas are emphasized: immunology of diabetes and islet transplantation, neuroendocrinology, cell signaling, and developmental study of bone and gonad. All areas are at the forefront of national priorities in endocrine research. We propose again to support 3 M.D. and 3 Ph.D. trainees annually for 2-3 years each. All trainees will be individually mentored throughout their fellowships. A formal mentoring committee will continue to monitor each trainee's progress. A recruitment initiative to attract undergraduate medical students directly to the program will be continued and allow the start of research during residency. M.D. trainees will have access to graduate school coursework in molecular and cellular biology and Ph.D. trainees will attend special seminars to enhance their knowledge of the translation of basic research to the clinic. Program faculty comprise a lean 'core' of 18 scientists, each of whom is an extramurally funded authority in one of the areas of emphasis. We believe that the proposed organizational and educational program will continue to enhance the research experience of our trainees and address the nation's need for committed investigators and academics in these important areas of medical and research need.