Bioaerosols in Midwest Greenhouses and Respiratory Symptoms Among the Workers

中西部温室中的生物气溶胶和工人的呼吸道症状

• 批准号: 7642428
• 负责人: ATIN ADHIKARI
• 金额: $ 8.35万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7642428
• 关键词: Bioaerosols; Midwest; Greenhouses; Respiratory; Symptoms

DESCRIPTION (provided by applicant): Estimated economic impacts of the US Green Industry are 1,964,339 jobs, and $147.8 billion in output, of which 27% is represented by the greenhouse and nursery sector. Little research has been conducted so far in the United States on the exposure to respiratory sensitizer bioaerosols in greenhouses and their association with allergic rhinitis, occupational asthma, and other respiratory health problems of the workers. The goal of this study is to collect pilot data for an ensuing R01 proposal addressing exposure risks to respiratory health hazards, prevalence of respiratory symptoms among the Green Industry workers, and exploring intervention methods at the same time considering the possible protective effect of endotoxin and (1?3)-¿-D-glucan exposures against allergen sensitizations. Workers' exposures to airborne pollen, molds, bacteria, actinomycete, endotoxin, and (1?3)-¿-D-glucans in three Midwest greenhouses will be investigated during spring and winter and the concentrations will be compared with reported levels in the greenhouses of other countries, other agricultural workplaces, and nearby ambient air. The work-shift average and task-specific exposures to bioaerosols will be studied by using inhalable samplers during different work tasks. To understand the sources of bioaerosols, surface sampling of biological particles on the floors and hard surfaces will be performed. Moreover, potential source strengths of these surfaces for aerosolizing biological particles will be determined by Fungal Spore Source Strength Tester developed by our research group. Environmental parameters including temperature, relative humidity, and wind velocity will be measured during each air sampling experiment. The correlation between different environmental variables and bioaerosol exposure levels will be determined. To understand the prevalence of rhinitis, wheezing, respiratory allergies, asthma, and other respiratory symptoms among the greenhouse workers and its association with different greenhouse work tasks and bioaerosol levels, a preliminary questionnaire survey will be conducted involving 45 workers and 15 control subjects from three greenhouses. The proposed project is relevant for the NORA2's 'Agriculture, forestry, and fishing' sector group, three cross-sector programs (Health hazard evaluation, Respiratory diseases, and Communications and information dissemination) and two coordinated emphasis areas.

描述（由适用提供）：美国绿色行业的估计经济影响为1,964,339个工作岗位和1478亿美元的产出，其中27％由温室和托儿所代表。到目前为止，在美国迄今为止，关于温室中呼吸道传感器生物溶质的暴露及其与工人的过敏性鼻炎，占用的呼吸道健康问题的相关性很少。这项研究的目的是为随后的R01提案收集试验数据，以解决呼吸健康危害的风险，绿色行业工人中呼吸症状的患病率以及探索干预措施 方法同时考虑了内毒素的可能保护作用和（1？3） - d-glucan对过敏原传感器的暴露。工人对空气传播的花粉，模具，细菌，放线菌，内毒素和（1？3） - d-Glucans在三个中西西部温室中的曝光，将在春季和冬季进行研究，并将其浓度与其他国家（其他农业工作场所）的绿色小屋中的报道水平进行比较。在不同的工作任务中，将研究对生物溶质的工作班平均值和特定于任务的暴露。为了了解生物溶质的来源，将进行地板和硬表面上生物颗粒的表面采样。此外，这些表面的潜在源强度将由我们的研究组开发的真菌孢子源强度测试仪确定。在每个空气采样实验期间，将测量包括温度，相对湿度和风速在内的环境参数。将确定不同环境变量与生物Aerosol暴露水平之间的相关性。为了了解温室工作者中鼻炎，惠灵，呼吸过敏，哮喘和其他呼吸道症状的患病率，以及与不同的温室工作任务和生物美感水平的关联，将进行45名工人调查 来自三个温室的15名控制受试者。拟议的项目与NORA2有关 “农业，林业和捕鱼”部门集团，三个跨部门计划（健康危害评估， 呼吸道疾病，传播和信息传播）和两个协调的重点区域。