Shared Resources-Clinical Research Services
共享资源-临床研究服务
基本信息
- 批准号:7673442
- 负责人:
- 金额:$ 14.1万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:
- 资助国家:美国
- 起止时间:至
- 项目状态:未结题
- 来源:
- 关键词:AddressApplications GrantsAreaBasic ScienceBiometryBiostatistics CoreBiostatistics Shared ResourceCancer CenterClinicalClinical ResearchClinical SciencesClinical ServicesClinical TrialsConsultationsCore FacilityDataData AnalysesDoctor of PhilosophyEnsureEpidemiologistEpidemiologyEvaluationFacultyFundingLeadershipMalignant NeoplasmsMedicineMethodologyMethodsMonitorNumbersOncologistPeer ReviewPopulation SciencesPositioning AttributeProcessProtocols documentationPublic HealthRangeRecruitment ActivityReportingRequest for ApplicationsResearchResearch ActivityResearch DesignResearch InfrastructureResearch PersonnelResearch Project GrantsResolutionResource SharingResourcesReview CommitteeServicesStrategic PlanningStudentsTimeTrainingTranslational ResearchWorkWritingfrontiermemberprogramsprospectivestatistical servicetool
项目摘要
The Biostatistics Shared Resource provides support for the three broad major programmatic areas of YCC:
clinical science; basic science; and population science. The services provided include: biostatistical
support to research projects, assistance with the statistical and research aspects of new research projects
and grant applications, data analysis, and training/As such, this core is vital to clinical trials/study design
process. Additionally, this core has the major responsibility to support the protocol review and monitoring
process of the YCC. Thus, this Shared Resource provides critical support for the complete spectrum of
statistical services, from study design through the final research report writing. In late 2005, Dr. Theodore
Holford accepted the position as Director of this core facility. Dr. Holford will work closely with Dr. Daniel
Zelterman, who serves as Co-Director of the Biostatistics Shared Resource. The Biostatistics Shared
Resource is Cancer Center Managed and provides statistical support and data analysis to YCC in the form
of active consultation with six Ph.D. statisticians dedicated to the YCC. The 2 major criticisms of the
previous renewal have been addressed. Specifically, creation of a Biostatistics Clinical Studies Group,
chaired by Dr. Holford, ensures that biostatistical expertise applied to Protocol Review Committee
evaluation of prospective clinical trials will be completely distinct from that involved in the particular study's
design and subsequent analysis of accrued data. In addition, the biostatistical staff has been significantly
expanded, to provide full coverage for the marked increase in investigator-initiated clinical research
activities, resulting from the recruitment of a large number of new clinical researchers. Over the past 2
years, 11 new investigative clinical oncologists have joined the YCC, and their clinical trials efforts have led
to a 56% increase in the required biostatistical support. In order to support these increased needs, the
faculty biostatistician staff of this Shared Resource has grown from 2 to 7. In this renewal application, we
are requesting 1.75 FTE for the next period of funding.
In 2005 100%, or 42, users were YCC members (65.5% Peer reviewed) from all 8 of the YCC research
programs
生物统计共享资源为生物统计中心的三大主要规划领域提供支持:
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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William K. Kelly其他文献
Irradiation of prostate cancer alters circulating small extracellular vesicle functions
前列腺癌的照射改变了循环小细胞外囊泡的功能
- DOI:
10.1038/s41598-025-03329-5 - 发表时间:
2025-07-02 - 期刊:
- 影响因子:3.900
- 作者:
Aejaz Sayeed;Vaughn Garcia;Cecilia E. Verrillo;Rachel M. DeRita;Md Niamat Hossain;Shiv Ram Krishn;Samuel Sey;Christopher D. Shields;Adrian D. Altieri;Qin Liu;Khalid Sossey-Alaoui;William K. Kelly;Lucia R. Languino - 通讯作者:
Lucia R. Languino
Histone deacetylases and cancer: causes and therapies
组蛋白去乙酰化酶与癌症:原因与疗法
- DOI:
10.1038/35106079 - 发表时间:
2001-12-01 - 期刊:
- 影响因子:66.800
- 作者:
Paul A. Marks;Richard A. Rifkind;Victoria M. Richon;Ronald Breslow;Thomas Miller;William K. Kelly - 通讯作者:
William K. Kelly
1139: Predicting Time to Metastatic Progression from Biochemical Recurrence after Radical Prostatectomy
- DOI:
10.1016/s0022-5347(18)35295-9 - 发表时间:
2005-04-01 - 期刊:
- 影响因子:
- 作者:
Zohar A. Dotan;Fernando J. Bianco;Peter T. Scardino;James A. Eastham;Paul A. Fearn;Andrew J. Stephenson;Howard I. Scher;William K. Kelly;Michael W. Kattan - 通讯作者:
Michael W. Kattan
William K. Kelly的其他文献
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{{ truncateString('William K. Kelly', 18)}}的其他基金
Genomic profiling of single circulating tumor cells in the precision medicine of metastatic prostate cancer
转移性前列腺癌精准医疗中单个循环肿瘤细胞的基因组分析
- 批准号:
10299248 - 财政年份:2021
- 资助金额:
$ 14.1万 - 项目类别:
Genomic profiling of single circulating tumor cells in the precision medicine of metastatic prostate cancer
转移性前列腺癌精准医疗中单个循环肿瘤细胞的基因组分析
- 批准号:
10447655 - 财政年份:2021
- 资助金额:
$ 14.1万 - 项目类别:
Targeting Cell Cycle Alterations to Improve Treatment for Advanced Prostate Cancer
针对细胞周期改变改善晚期前列腺癌的治疗
- 批准号:
10212337 - 财政年份:2017
- 资助金额:
$ 14.1万 - 项目类别:
Targeting Cell Cycle Alterations to Improve Treatment for Advanced Prostate Cancer
针对细胞周期改变改善晚期前列腺癌的治疗
- 批准号:
9975104 - 财政年份:2017
- 资助金额:
$ 14.1万 - 项目类别: