Molecular characterisation of host cell targets of human pathogenic viruses and evaluating their potential as novel therapeutic targets.
Molecular characterisation of host cell targets of human pathogenic viruses and evaluating their potential as novel therapeutic targets.
人类病原病毒宿主细胞靶标的分子特征并评估其作为新治疗靶点的潜力。
批准号：
nhmrc : 1037092
负责人：
Dr Mohamad Aljofan
金额：
$20.53万
依托单位：
依托单位国家：
澳大利亚
项目类别：
Early Career Fellowships
财政年份：
2012
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2012-01-01 至 2014-12-31
中文摘要
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英文摘要
There are currently no therapeutics to treat victims of Hendra, Nipah or Rabies virus infections, which account for > 50,000 deaths/yr worldwide. Through not fully understood mechanisms, these viruses affect the functions of specific cellular proteins in order to inhibit the host immune system, a process essential to their pathogenicity. We aim to characterise the mechanisms underlying viral inhibition of host immunity and evaluate their potential as novel targets to develop urgently needed therapeutics against these deadly pathogens.
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