Developmental Research program

发展研究计划(DRP)旨在提供资金，以启动有前途的 以脑瘤为重点的翻译研究。将高度优先考虑将产生 临床相关假说，旨在降低脑肿瘤的发病率或死亡率或改善 脑肿瘤患者的生活质量。至少每年一次，创新翻译大脑的建议 肿瘤研究将在德克萨斯医学中心的所有机构中征集。预计 一些申请者在准备成功的研究提案方面没有广泛的经验； 因此，DRP联席主任将帮助调查人员制定具体的目标和研究计划，这些目标和计划包括 翻译性质，具有现实和适当的预算。因此，除了发展有希望的 对于孢子计划的研究项目，DRP也将是一项主要的教育活动，将进一步 促进脑癌创新翻译研究概念的启动和发展。 孢子执行委员会将筛选适合孢子资格的提案，使用 客观标准。选定的建议随后将由成员进行科学审查和确定优先顺序 孢子外部咨询委员会；将对将获得资助的研究项目进行最终选择 在这些审查的基础上。将允许两年的资助期，并为 在对获奖者的书面进度报告进行令人满意的审查后进行第二年。其他内容 如果认为多一年的工作将导致独立的同行审查，则可提供资金 提供资金和/或显著加强脑肿瘤的诊断或治疗；为此提出请求 额外资金将由孢子执行委员会和外部机构非常仔细地审查 顾问委员会。作为我们继续努力扩大德克萨斯大学脑瘤研究的一部分 安德森癌症中心和预期这种孢子的应用，开发研究 征集了项目；四个项目被认为是最具潜力和符合 孢子的翻译重点包括在这里，代表那些将被考虑资助的 从孢子计划的第一年开始。这些项目说明了对以下方面的兴趣的广度和深度 我们机构的脑瘤转译研究。

The Developmental Research Program (DRP) is designed to provide funding to initiate promising translational studies with a focus on brain tumors. High priority will be given to projects that will generate clinically-relevant hypotheses aimed at reducing the morbidity or mortality of brain tumors or improving the quality of life of patients with brain tumors. At least annually, proposals for innovative translational brain tumor research will be solicited throughout all institutions in the Texas Medical Center. It is anticipated that some applicants will be without extensive experience in preparing successful research proposals; therefore, the DRP Co-Directors will help investigators formulate specific aims and research plans that are translational in nature, with realistic and appropriate budgets. Thus, in addition to developing promising research projects for the SPORE program, the DRP will also be a major educational activity that will further enhance the initiation and development of innovative translational research concepts in brain cancer. The SPORE Executive Committee will screen proposals for appropriate SPORE qualifications using objective criteria. The selected proposals will then undergo scientific review and prioritization by members of the SPORE External Advisory Board; final selection of the research projects to be funded will be made on the basis of these reviews. A two-year funding period will be allowed, with allocation of funds for the second year to be made after satisfactory review of a written progress report from the awardee. Additional funding may be granted, if it is felt that an additional year of work will lead to independent peer-reviewed funding and/or lead to significant enhancement in diagnosis or treatment of brain tumors; requests for this additional funding will be very carefully reviewed by the SPORE Executive Committee and External Advisory Board. As part of our continuing efforts to expand brain tumor research at The University of Texas M. D. Anderson Cancer Center and in anticipation of this SPORE application, developmental research projects were solicited; the four projects considered to be of highest potential and consistent with the translational focus of the SPORE are included here and represent those that will be considered for funding to begin in Year 1 of the SPORE program. These projects illustrate the breadth and depth of interest in brain tumor translational research at our institution.