C2: Biostatistics

生物统计核心由具有统计专业知识的人员组成。生物统计核心的目标是 与孢子调查人员和其他核心资源科学家合作，提高 这项研究是在密歇根大学的头颈孢子实验室进行的。核心人员已经被 被选中是因为他们在生物统计学相关领域的专业知识，以及他们的经验和 &lt；现在患有头颈癌。 生物统计核心人员将与四个拟议项目中的每一个项目合作，将与 其他核心，也将期望与所有资助的发展奖互动，因此这一核心至关重要 对孢子很重要。来自核心的人员将在调查的所有阶段与调查人员互动 研究，从研究问题的表述开始，一直到实验设计阶段 和数据收集阶段，到数据分析和解释阶段，到编写报告和传播 结果。生物统计学专业知识不可或缺的两个领域是实验设计和数据 分析。从这项提案中可以明显看出，核心人员在 设计拟议的实验并规划数据分析。 核心的具体目标是： 1)协助研究人员设计临床和实验室实验 2)协助调查人员分析和解释来自临床和实验室实验的数据 并在撰写科学手稿时向科学工作者传递头颈部癌孢子的研究结果 社区。 3)开展生物统计学翻译研究，开发与头颈部相关的方法学 癌症。

The Biostatistics Core consists of personnel with statistical expertise. The goal of the Biostatistics Core is to collaborate with SPORE investigators and other core resource scientists to enhance the quality of the research undertaken in the University of Michigan Head and Neck SPORE. The Core personnel have been chosen because of their expertise in relevant areas of Biostatistics and because of their experience and <nowledge of Head and Neck cancer. Biostatistics core personnel will collaborate with every one of the four proposed projects, will interact with the other cores and also will expect to interact with all funded development awards, and thus this core is crucially important to the SPORE. Personnel from the core will interact with the investigators in all stages of the research, beginning with the formulation of the research question, through the experimental design stage and data collection stage, to data analysis and interpretation, to the writing of reports and dissemination of results. Two areas where biostatistical expertise is indispensable are in experimental design and data analysis. It will be apparent from this proposal that Core personnel have played a significant role in designing the proposed experiments and in planning the data analysis. The Specific Aims of the core are to: 1) Assist investigators in the design of clinical and laboratory experiments 2) Assist investigators in the analysis and interpretation of data from clinical and laboratory experiments and in writing of scientific manuscripts relaying Head and Neck cancer SPORE results to the scientific community. 3) Undertake translational biostatistics research to develop methodology relevant to Head and Neck cancer.