C2: Biostatistics

生物统计学核心由具有统计学专门知识的人员组成。生物统计学核心的目标是 与SPORE调查人员和其他核心资源科学家合作，提高 密歇根大学头颈部孢子研究所进行的研究。核心人员已经 选择他们是因为他们在生物统计学相关领域的专业知识和他们的经验， <头颈部癌的治疗。 生物统计学核心人员将与四个拟议项目中的每一个项目合作，将与 其他核心，也将期望与所有资助的发展奖互动，因此这个核心是至关重要的 对孢子很重要。核心人员将在调查的所有阶段与调查人员互动， 研究，从研究问题的制定开始，通过实验设计阶段 数据收集阶段，到数据分析和解释，到编写报告和传播 结果生物统计学专业知识不可或缺的两个领域是实验设计和数据 分析.从这一建议中可以明显看出，核心人员在以下方面发挥了重要作用： 设计拟议的实验和规划数据分析。 核心的具体目标是： 1)协助研究者设计临床和实验室实验 2)协助研究者分析和解释临床和实验室实验数据 并在撰写科学手稿时将头颈癌孢子结果传递给科学家， 社区 3)进行转化生物统计学研究，以开发与头颈部相关的方法 癌

The Biostatistics Core consists of personnel with statistical expertise. The goal of the Biostatistics Core is to collaborate with SPORE investigators and other core resource scientists to enhance the quality of the research undertaken in the University of Michigan Head and Neck SPORE. The Core personnel have been chosen because of their expertise in relevant areas of Biostatistics and because of their experience and <nowledge of Head and Neck cancer. Biostatistics core personnel will collaborate with every one of the four proposed projects, will interact with the other cores and also will expect to interact with all funded development awards, and thus this core is crucially important to the SPORE. Personnel from the core will interact with the investigators in all stages of the research, beginning with the formulation of the research question, through the experimental design stage and data collection stage, to data analysis and interpretation, to the writing of reports and dissemination of results. Two areas where biostatistical expertise is indispensable are in experimental design and data analysis. It will be apparent from this proposal that Core personnel have played a significant role in designing the proposed experiments and in planning the data analysis. The Specific Aims of the core are to: 1) Assist investigators in the design of clinical and laboratory experiments 2) Assist investigators in the analysis and interpretation of data from clinical and laboratory experiments and in writing of scientific manuscripts relaying Head and Neck cancer SPORE results to the scientific community. 3) Undertake translational biostatistics research to develop methodology relevant to Head and Neck cancer.