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Small Animal Imaging Core

Small Animal Imaging Core
小动物成像核心
批准号:
7490309
负责人:
Craig J Galban
金额:
$23.8万
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-04-01 至 2013-03-31

项目摘要

项目成果

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中文摘要
翻译
核心B:动物成像核心将协助所有细胞、组织的成像研究和分析 所有项目的标本和小鼠肿瘤模型。核心人员将提供以下服务:(A)确定 并执行数据采集/成像序列;(B)协助动物为成像做准备;(C) 在CM I成像系统上进行所有数据收集;(D)数据处理、图像重建和图像 登记;(E)原始数据的安全存档和重建数据到数字图像的网络传输 处理实验室;(F)安排成像实验;和(G)为方案提供支持 研究人员在影像实验中的技术设计。这些服务在一定程度上是在“临床”之后设计的 因为连续的、大容量的动物扫描是成功的多样化的关键 ICMIC项目。将进行超过2400小时的生物发光、荧光和磁共振成像 五年多了。加尔班博士将担任核心B董事。加尔班博士拥有丰富的小型企业经验 动物成像研究。实验室经理和实验室主任将协助日常运作。 和技术发展。技术支持将由分子成像中心(CMI)提供。 公共卫生:总体/这一核心将提供所需的服务,以推进这一总体使命 ICMIC应用程序,用于开发分子成像工具和应用程序,最终影响患者护理。
英文摘要
CORE B: The Animal Imaging Core will assist will all of the imaging studies and analysis of cells, tissue specimens and mouse tumor models for all projects. Core personnel will provide these services: (a) define and implement data acquisition/imaging sequences; (b) assist with animal preparation for imaging; (c) perform all data collection on CM I imaging systems; (d) data processing, image reconstruction and image registration; (e) security archival of raw data and network transfer of reconstructed data to the Digital Image Processing Laboratory; (f) scheduling of imaging experiments; and (g) provide support to Program Investigators in technical design of imaging experiments. These services designed, in part, after a "clinical imaging service" model since continual, high-volume animal scanning is essential for success the diverse ICMIC Projects. More than 2400 hours of bioluminescence, fluorescence and MR imaging will be performed over five years. Dr. Galban will serve as Core B Director. Dr. Galban has extensive experience in small animal imaging research. A Laboratory manager and the DIPL director will aid with day-to-day operations and technique development. Technician support will be provided by the Center for Molecular Imaging (CMI). Public Health: Overall/this Core will provide the required services for forwarding the overall mission of this ICMIC application to develop molecular imaging tools and applications for ultimately impacting patient care.
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