Molecular characteristation of the adiponectin receptors, AdipoR1 and AdipoR2: Identifying strategies to enhance adiponectin sensitivity and reduce cardiometabolic disease.
Molecular characteristation of the adiponectin receptors, AdipoR1 and AdipoR2: Identifying strategies to enhance adiponectin sensitivity and reduce cardiometabolic disease.
脂联素受体 AdipoR1 和 AdipoR2 的分子特征：确定增强脂联素敏感性和减少心脏代谢疾病的策略。
批准号：
nhmrc : 1074074
负责人：
金额：
$22.31万
依托单位：
依托单位国家：
澳大利亚
项目类别：
Early Career Fellowships
财政年份：
2014
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2014-01-01 至 2019-12-31
来源：
中文摘要
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英文摘要
Obesity and Type 2 diabetes (T2D) increase risk of cardiovascular disease (CVD), a leading cause of death in Australia. New drugs are required to reduce the health risks and financial burden of these diseases. Targeting hormone receptors to reduce fat storage in liver and skeletal muscle in obesity may improve insulin sensitivity and reduce blood sugar levels and therefore reduce CVD risk. This research will study how these receptors function in order to develop new drugs to reduce CVD risk.
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