Emory University PD Neuroprotection Clinical Trial Center

埃默里大学运动障碍项目和综合性帕金森疾病中心 已经证明有必要的资源和基础设施来继续成为帕金森氏症患者 疾病神经保护临床试验中心。我们有进行神经保护试验的经验， 事实上，已经作为加州大学的分包商参加了Net-PD无效性研究2试验 伯明翰的阿拉巴巴(UAB)。这项提议的目的是将我们的中心从一个分包地点恢复到 它最初作为一个独立网站的地位。我们在这项研究和其他许多研究中都取得了成功 部分原因是我们地区目前估计有5万人被诊断为帕金森氏症 以及我们地区每年估计新诊断的5000名患者。人口统计数据 埃默里大学所服务地区的特点允许招收不同种族的学生 研究患者的群体。埃默里大学的研究和治疗项目 帕金森氏症有必要的空间来舒适有效地进行临床试验，准备 并处理实验室样本，并安全保密地维护研究、药物和文档。 一支经验丰富的临床试验团队目前已经到位，以确保研究以一种 这使得能够准确、高效和及时地收集数据。临床试验工作人员都收到了 埃默里大学机构审查委员会提供的进行临床试验的培训和认证 接受过培训，目前遵循良好的临床实践指南，以确保安全和保护 研究参与者的数量。首席调查员Jorge L.Juncos博士在以下方面拥有丰富的经验 开发、进行和监测临床试验，并在康复方面有良好的记录 病人。该中心目前与美国佐治亚州帕金森病协会密切合作， 通知并招募新患者参加这些研究。总而言之，这项提案应该证明这样一个事实 我们的中心已经证明有能力作为一个优秀的调查和招聘网站 这些美国国立卫生研究院赞助了帕金森病患者的神经保护试验。

The Emory University Movement Disorders Program and the Comprehensive Parkinson's Disease Center has proven to have in place the necessary resources and infrastructure to continue to be a Parkinson's Disease Neuroprotection Clinical Trial Center. We have experience in conducting neuroprotective trials and are in fact already participating in the NET-PD Futility Study 2 trial as a subcontractor to University of Alababa in Birmingham (UAB). The aim of this proposal in to revert our center from a subcontracting site to its original status as an independent site. We have been a successful site in this and many other studies in part because of the estimated 50,000 persons currently diagnosed with Parkinson's disease in our region and the estimated 5,000 patients that are newly diagnosed each year in our region. The demographic characteristics of the area served by Emory University allows for the recruitment of an ethnically diverse population of study patients. The Emory University programs involved in the research and treatment of Parkinson's Disease have the necessary space to comfortably and efficiently conduct clinical trials, prepare and process lab specimens and securely and confidentially maintain study medication and documentation. An experienced clinical trial team is currently in place to assure that the studies are conducted in a manner which allows for the accurate, efficient and timely collection of data. The Clinical Trial Staff have all received training and certification to conduct clinical trials from the Emory University Institutional Review Board and have been trained and currently follow Good Clinical Practice Guidelines to assure the safety and protection of study participants. The Principal Investigator, Dr. Jorge L. Juncos, has extensive experience in developing, conducting and monitoring clinical trials and an excellent track record in the recuitment of patients. The Center currently works closely with the American Parkinson Disease Association of Georgia to inform and recruit new patients for these studies. In conclusion this proposal should evidence the fact that our center has demonstrated is capacity for serving as an excellent investigative and recruitment site for these NIH sponsored trials in neuroprotection in PD.