Developing and Improving Institutional Animal Resources (G20)

简介(由申请者提供)：埃默里大学致力于成为一所领先的发现和研究机构。埃默里大学的研究蓬勃发展，因为我们在国立卫生研究院获得拨款的大学中的机构排名自1996年以来上升了10位(从第32位)到2005年的第22位。研究企业的这种增长主要是通过PHS赞助的研究，以及在使用动物模型的情况下，用老鼠进行的。鉴于这种动态，我们常驻科学家的生产力和留住以及招募顶级生物医学研究人员的关键是研究资源，包括以低成本支持大量小鼠。在过去的6年里，埃默里大学总共建造或翻新了81,829 GSF的动物研究设施，使总容量增加了76%，达到146,424 GSF，总成本为24,788,797美元。为了补充这些资源，我们寻求购买15个啮齿动物通风笼子系统，每个系统可容纳140个笼子(840只小鼠)，并提供自动化供水，以最大限度地利用这种扩张势头以及由此产生的对更多老鼠笼子的相关需求。购买这些笼子将允许以更低的成本为埃默里调查人员提供更高密度的老鼠住所，并对NIH赠款的申请有显著好处。这些笼子系统将使每年节省高达122,640美元的成本传递给调查人员，并将直接支持158名科学家使用MICE的工作，其中直接成本为4,060万美元，目前已获得208项小灵通拨款，34项小灵通拨款为700万美元。

DESCRIPTION (provided by applicant): Emory University seeks to advance as a leading institution in discovery and research. Research at Emory has flourished as our institutional rank among universities with NIH awarded grants has increased 10 places (from 32nd) since 1996 to 22nd in 2005. This growth in the research enterprise has been primarily through PHS sponsored research and, where animal models are used, with mice. Given this dynamic, the key to the productivity and retention of our resident scientists and recruitment of top tier biomedical investigators are research resources, including support for large numbers of mice at low cost. Emory University has in the past 6 years constructed or renovated a total of 81,829 GSF of animal research facilities increasing overall capacity by 76% to 146,424 GSF and at a total cost of $24,788,797. To compliment these resources, we seek to acquire 15 rodent ventilated caging systems with 140 cage (840 mouse) capacity each and automated water supply to build foremost upon this momentum of expansion and the associated need for more mouse caging that it has created. The purchase of these cages will allow for higher density mouse housing at lower cost for Emory investigators and with significant benefits to the application of NIH grant dollars. These caging systems will enable up to $122,640 annual cost savings passed on to investigators and will directly support the work of 158 scientists using mice with $40.6M direct costs in 208 currently funded PHS grants and with 34 PHS grants for $7M pending.