Developing and Improving Institutional Animal Resources (G20)

描述（由申请人提供）：埃默里大学寻求推进作为一个领先的机构在发现和研究。埃默里大学的研究蓬勃发展，因为我们在NIH授予赠款的大学中的机构排名自1996年以来增加了10个位置（从第32位）到2005年的第22位。研究企业的这种增长主要是通过PHS赞助的研究以及使用动物模型的小鼠。鉴于这种动态，我们的驻地科学家的生产力和保留以及顶级生物医学研究人员的招聘的关键是研究资源，包括以低成本支持大量小鼠。埃默里大学在过去的6年中建造或翻新了81，829 GSF的动物研究设施，使总容量增加了76%，达到146，424 GSF，总成本为24，788，797美元。为了补充这些资源，我们寻求获得15个啮齿动物通风笼系统，每个笼容量为140个笼（840只小鼠），并配备自动供水系统，以最大限度地利用这一扩张势头及其产生的对更多小鼠笼的相关需求。购买这些笼子将允许埃默里大学研究人员以更低的成本获得更高密度的小鼠住房，并对NIH拨款的应用产生重大影响。这些笼子系统将使每年节省高达122，640美元的成本转嫁给研究人员，并将直接支持158名科学家使用小鼠的工作，其中4060万美元的直接成本在208个目前资助的PHS赠款中，34个PHS赠款为700万美元。

DESCRIPTION (provided by applicant): Emory University seeks to advance as a leading institution in discovery and research. Research at Emory has flourished as our institutional rank among universities with NIH awarded grants has increased 10 places (from 32nd) since 1996 to 22nd in 2005. This growth in the research enterprise has been primarily through PHS sponsored research and, where animal models are used, with mice. Given this dynamic, the key to the productivity and retention of our resident scientists and recruitment of top tier biomedical investigators are research resources, including support for large numbers of mice at low cost. Emory University has in the past 6 years constructed or renovated a total of 81,829 GSF of animal research facilities increasing overall capacity by 76% to 146,424 GSF and at a total cost of $24,788,797. To compliment these resources, we seek to acquire 15 rodent ventilated caging systems with 140 cage (840 mouse) capacity each and automated water supply to build foremost upon this momentum of expansion and the associated need for more mouse caging that it has created. The purchase of these cages will allow for higher density mouse housing at lower cost for Emory investigators and with significant benefits to the application of NIH grant dollars. These caging systems will enable up to $122,640 annual cost savings passed on to investigators and will directly support the work of 158 scientists using mice with $40.6M direct costs in 208 currently funded PHS grants and with 34 PHS grants for $7M pending.