Amblyopia in Astigmatic Children-Development & Treatment

散光儿童发育中的弱视

• 批准号: 7473866
• 负责人: Erin M Harvey
• 金额: $ 69.41万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-15 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7473866
• 关键词: Age; Age-Years; Amblyopia; Astigmatism; Blur; Child; Child Development; Clinical; Coma; Condition; Cornea; Development; Effectiveness; Eyeglasses; General Population; Goals; Guidelines; High Prevalence; Infant; Literature; Low Prevalence; Native Americans; Nursery Schools; Optics; Population; Prevention; Refractive Errors; Research; Research Personnel; Risk; School-Age Population; Time; Toddler; Tribes; United States Public Health Service; Visual; Visual Acuity; Visual system structure; deprivation; early childhood; experience; infancy; treatment effect; vision development; visual deprivation

The detrimental effects of uncorrected astigmatism on visual development are well documented: blur induced by uncorrected astigmatism results in visual deficits that persist despite optical correction. Partnership with the Tohono O'odham Nation, a Native American tribe with a high prevalence of high astigmatism has allowed researchers to conduct large-scale studies of preschool- and school-aged children with high astigmatism. However, little is known about the development of astigmatism and astigmatism- related amblyopia prior to age 3 years. The goals of the present study are: Goal 1. To document developmental changes in astigmatism and aberrations in infants and young children from a population with a high prevalence of high astigmatism. Goal 2. To determine the relation between quality of visual experience (quality of visual input) in astigmatic and non-astigmatic infants and toddlers and visual development (normal and abnormal/amblyopic). Goal 3. To determine the relation between spherical aberration and coma and corrected visual acuity in young children with and without high astigmatism. Goal 4. To determine the effectiveness of eyeglass treatment of astigmatism-related amblyopia in young children. The proposed study will provide unique and valuable information on the development of astigmatism and aberrations and their effects on visual development, will generate important clinical information to aid in the development of guidelines for treatment and prevention of astigmatism-related amblyopia in infancy and early childhood, and will provide a valuable public health service for a population whose children are at increased risk for the development of amblyopia.

未经矫正的散光对视觉发育的有害影响是有据可查的：模糊 未经矫正的散光会导致视力下降，即使进行了光学矫正仍会持续存在。 与Tohono O‘odham Nation建立伙伴关系，Tohono O’odham Nation是一个美洲原住民部落，高发率很高 散光使研究人员能够对学龄前儿童和学龄儿童进行大规模研究 有高度散光。然而，人们对散光和散光的发展知之甚少。 3岁以前的相关弱视。本研究的目标是： 目标1.记录婴幼儿散光和像差的发育变化 来自高度散光患病率高的人群的儿童。 目标2.确定视觉体验质量(视觉输入质量)与 散光和非散光的婴幼儿和幼儿的视觉发育(正常和 异常/弱视)。 目标3：确定球差、昏迷和矫正视力之间的关系 有高度散光和无高度散光的幼儿。 目标4：确定散光相关性弱视的眼镜治疗效果。 年幼的孩子。 这项拟议的研究将提供有关散光发展的独特和有价值的信息和 像差及其对视觉发育的影响，将产生重要的临床信息，以帮助 制定治疗和预防婴幼儿散光相关性弱视的指南 儿童早期教育，并将为儿童年龄在 患弱视的风险增加。