ETHANOL EFFECTS ON PRIMATE EMBRYONIC CELLS

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: Treatment of liver disease with orthotopic liver transplantation carries considerable morbidity and mortality. Moreover, due to organ shortages, thousands of people die each year without getting transplanted. Therefore, safer and more convenient alternative therapies will benefit many people requiring liver transplantation. Studies are currently in progress differentiating rhesus embryonic stem cells obtained from the ONPRC towards a hepatocyte lineage.