ETHANOL EFFECTS ON PRIMATE EMBRYONIC CELLS

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 目的：原位肝移植治疗肝病有相当高的发病率和死亡率。 此外，由于器官短缺，每年有数千人在没有得到移植的情况下死亡。 因此，更安全，更方便的替代疗法将使许多需要肝移植的人受益。 目前正在进行将从ONPRC获得的恒河猴胚胎干细胞分化为肝细胞谱系的研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: Treatment of liver disease with orthotopic liver transplantation carries considerable morbidity and mortality. Moreover, due to organ shortages, thousands of people die each year without getting transplanted. Therefore, safer and more convenient alternative therapies will benefit many people requiring liver transplantation. Studies are currently in progress differentiating rhesus embryonic stem cells obtained from the ONPRC towards a hepatocyte lineage.