ETHANOL EFFECTS ON PRIMATE EMBRYONIC CELLS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 目的：原位肝移植治疗肝病具有相当高的发病率和死亡率。此外，由于器官短缺，每年有数千人在没有移植的情况下死亡。因此，更安全、更方便的替代疗法将使许多需要肝移植的人受益。目前正在进行将从ONPRC获得的恒河猴胚胎干细胞分化为肝细胞系的研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: Treatment of liver disease with orthotopic liver transplantation carries considerable morbidity and mortality. Moreover, due to organ shortages, thousands of people die each year without getting transplanted. Therefore, safer and more convenient alternative therapies will benefit many people requiring liver transplantation. Studies are currently in progress differentiating rhesus embryonic stem cells obtained from the ONPRC towards a hepatocyte lineage.