CORRELATION ANALYSIS BETWEEN THE INCIDENCE OF ALZHEIMER'S DISEASE AND AGE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究计划的总体目标是了解AD和AMD之间的联系。 总的假设是，由于淀粉样蛋白前体代谢的共同改变，AD和AMD具有相似的病因学途径。本研究的目的是获得初步数据，为更大规模的临床相关问题研究做准备。长期目标是开发一套敏感的生物标志物，包括电生理学、解剖学和生物化学标志物，以便早期发现这两种毁灭性疾病。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall objective of this research program is to understand the link between AD and AMD. The overall hypothesis is that AD and AMD share a similar etiological pathway due to a common alteration in the metabolism of amyloid protein precursor. The purpose of this study is to obtain preliminary data in preparation for a larger study of this clinically relevant problem. The long-term goal would be to develop a set of sensitive biomarkers, comprised of electrophysiological, anatomical and biochemical markers to allow for an early detection of these two devastating diseases.