NATRIURETIC PEPTIDE RESPONSE TO SALINE INFUSION

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 心房利钠肽（ANP）和脑利钠肽（BNP）由心脏分泌，以响应心壁应力增加。 超重和肥胖个体的血浆促钠尿肽水平显著低于瘦个体。 我们的研究旨在确定是否利钠肽，超声心动图和生理盐水输注的代谢反应不同瘦的个人，肥胖的个人之前，和肥胖的个人体重减轻胃旁路手术后。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) are secreted by the heart in response to increased cardiac wall stress. Overweight and obese individuals have substantially lower plasma natriurietic peptide levels than lean individuals. Our study aims to determine if the natriuretic peptide, echo, and metabolic responses to saline infusion differ between lean individuals, obese individuals before, and obese individuals after weight loss from gastric bypass surgery.