A PILOT STUDY EVALUATING THE PHARMACOKINETIC INTERACTION BETWEEN LEVETIRACETA
A PILOT STUDY EVALUATING THE PHARMACOKINETIC INTERACTION BETWEEN LEVETIRACETA
批准号:
7603607
负责人:
Suzette Laroche
金额:
$0.42万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-12-01 至 2007-09-16
中文摘要
这个子项目是许多研究子项目中利用
资源由NIH/NCRR资助的中心拨款提供。子项目和
调查员(PI)可能从NIH的另一个来源获得了主要资金,
并因此可以在其他清晰的条目中表示。列出的机构是
该中心不一定是调查人员的机构。
这是一项开放的、非随机的药代动力学先导性研究,旨在评估左乙拉西坦(Lev)对洛比那韦/利托那韦(LPV/r)的药代动力学的影响。主要目的是确定联合给药对接受该药治疗的HIV患者的稳态药代动力学LPV/r的影响。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
This is an open label, non-randomized, pharmacokinetic pilot study designed to evaluate the effects of levetiracetam (LEV) on the pharmacokinetics of lopinavir/ritonavir (LPV/r). The primary aim is to identify the effect of LEV co-administration on the steady state pharmacokinetics LPV/r among HIV patients being treated with this agent.
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