FASEB summer research conferences on Virus Structure and Assembly

FASEB 病毒结构与组装夏季研究会议

• 批准号: 7908294
• 负责人: Mavis Agbandje-Mckenna
• 金额: $ 1.5万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7908294
• 关键词: Address; Biochemical; Biotechnology; Cells; Cellular biology; Complex; Development; Discipline; Funding; Gene Delivery; Genetic; Investigation; Molecular; Molecular Biology; Process; Request for Applications; Research; Research Personnel; Structure; System; Therapeutic; Viral; Virus; macromolecule; meetings; nanomaterials; symposium; vector; virus development

DESCRIPTION (provided by applicant): The assembly of an infectious virus within the cell is a complex process that requires the temporal and coordinated activities of numerous macromolecules of both viral and host origin. Understanding these interactions at the molecular level is essential to the development of effective anti-viral therapeutics and to harnessing these relatively simple systems for use as corrective gene delivery vectors and as nanomaterials. A comprehensive interrogation of these systems is best served by a multi-discipline approach that includes genetic, molecular biology, cell biology, structural, biochemical and biophysical approaches. The FASEB Summer Research Conference on Virus Structure and Assembly has served as a key meeting for researchers in these diverse disciplines to gather and discuss cutting edge results and major breakthroughs in the field. Indeed, many new anti-viral therapies are the direct result of basic scientific investigations, which has been the emphasis of past FASEB conferences. This application requests funds to support this prestigious and important meeting.) Understanding how an infectious virus assembles in the cell is essential to developing new anti-viral therapeutics and to developing viral systems for biotechnology applications. This application seeks support for the FASEB Summer Research Conference on Virus Structure and Assembly, a key scientific meeting that addresses diverse issues in virus development. )

描述（由申请人提供）：传染性病毒在细胞内的组装是一个复杂的过程，需要来自病毒和宿主的大量大分子的时间和协调活动。在分子水平上理解这些相互作用对于开发有效的抗病毒疗法以及利用这些相对简单的系统作为纠正性基因传递载体和纳米材料至关重要。对这些系统的全面研究最好采用多学科方法，包括遗传、分子生物学、细胞生物学、结构、生化和生物物理学方法。FASEB关于病毒结构和组装的夏季研究会议为这些不同学科的研究人员聚集和讨论该领域的前沿成果和重大突破提供了重要会议。事实上，许多新的抗病毒疗法是基础科学研究的直接结果，这一直是过去FASEB会议的重点。这个申请请求资金来支持这个有声望和重要的会议。了解传染性病毒如何在细胞内组装对于开发新的抗病毒疗法和开发用于生物技术应用的病毒系统至关重要。本申请寻求FASEB夏季病毒结构和组装研究会议的支持，这是一个解决病毒发展中各种问题的关键科学会议。