Milwaukee Clinical Site Hub

密尔沃基临床中心中心

• 批准号: 7807900
• 负责人: TOM Paul AUFDERHEIDE
• 金额: $ 19.41万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-03 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7807900
• 关键词: Accident and Emergency department; Acute; Adult; Architecture; Area; Award; Cardiac; Caring; Childhood; Clinical; Clinical Research; Clinical Trials; Collaborations; Commit; Communities; Community Healthcare; Community Hospitals; Contracts; County; Critical Care; Data; Emergency Medicine; Emergency Situation; Emergency medical service; Emergency treatment; Enrollment; Faculty; Foundations; Funding; Future; Goals; Health Personnel; Hospital Departments; Hospital Units; Hospitals; Housing; Human Resources; Informed Consent; Institution; Intervention; Joint Commission on Accreditation of Healthcare Organizations; Leadership; Medical; Medical Records; Medicine; Methods; Modeling; Monitor; National Heart, Lung, and Blood Institute; National Institute of Neurological Disorders and Stroke; Neurologic; Neurological emergencies; Neurology; Neurosciences; Outcome; Paramedical Personnel; Patient Recruitments; Patients; Pediatric Hospitals; Pediatric Surgical Procedures; Physical Medicine; Principal Investigator; Protocols documentation; Qualifying; Radiology Specialty; Recruitment Activity; Research; Research Ethics Committees; Research Infrastructure; Research Personnel; Research Support; Resources; Resuscitation; Services; Site; Specialist; Stroke; System; Telemedicine; Testing; Time; Training Activity; Trauma; Wisconsin; base; clinical research site; cost; dissemination research; experience; human subject protection; innovation; interest; medical schools; member; nervous system disorder; neurosurgery; pediatric trauma; professor; programs; trauma centers; treatment trial

DESCRIPTION (provided by applicant): The Department of Emergency Medicine of Froedtert Memorial Lutheran Hospital (FMLH) in collaboration with the Medical College of Wisconsin (MCW), and the Children's Hospital of Wisconsin are submitting this application for consideration to become a Clinical Site Hub (CSH) of the NINDS Emergencies Treatment Trials Network (NETT)(RFA-NS-06-009), to be known as the Milwaukee Clinical Site Hub (MCSH). Implementation of the selected NETT Network protocols will exploit the award-winning models of the Milwaukee County Emergency Medical Services (EMS) System and the nationally recognized Adult and Pediatric Trauma Centers housed at FMLH Adult Emergency Department and the adjoining Children's Hospital of Wisconsin (CHW) Pediatric Emergency Department, located on the MCW campus. Froedtert Memorial Lutheran Hospital, the Froedtert-MCW Stroke and Neurovascular Center, the Children's Hospital of Wisconsin, and the Milwaukee County EMS System will serve as the foundation of the Milwaukee Hub. Eight of the area's 15 affiliated paramedic-receiving community hospitals will serve as clinical spokes to support patient assessment and recruitment in real time and facilitate the dissemination of research results. These hospitals are members of the Milwaukee Emergency Medicine Research Consortium (MEMRC), an experienced and proven research association, distinguished by its long-standing infrastructure to support in- hospital and out-of-hospital research. The Milwaukee HUB will capitalize on its enormous existing research infrastructure to cost-effectively achieve the goals of the NETT to provide clinical leadership, research support, and local neurological expertise; coordinate IRB activities and human subjects protections; enter data, manage contracts, and oversee training activities. The principal investigator and key personnel are committed to actively partnering with the NETT Network and to disseminating the outcomes of the collective activities among community health care providers. The Milwaukee HUB aims to: 1) Leverage our existing infrastructure, established collaborations, and experience in conducting clinical research in the EMS and hospital settings (including exception to informed consent under emergency circumstances) to perform selected NETT clinical trials to enhance the efficient conduct of clinical research in neurological emergencies; 2) Orchestrate the participation of multiple emergency medicine departments and hospitals to expedite patient recruitment in neurological studies; 3) Engage a wide spectrum of investigators from MCW and participating hospitals; 4) Maximize our successful experience and capacity to recruit and retain a broad range of qualified subjects; 5) Cooperate with other NETT Hubs in facilitating the transfer of research; and 6) Coordinate with Network members in developing and testing innovative telemedicine methods involving off-site specialists in the care of neurological disorders in the emergency department.

描述（申请人提供）：Froedtert纪念路德医院（FMLH）急诊医学部与威斯康星州医学院（MCW）和威斯康星州儿童医院合作提交了本申请，以考虑成为NINDS紧急情况治疗试验网络（NETT）的临床研究中心（CSH）（RFA-NS-06 - 009），称为密尔沃基临床研究中心（MCSH）。选定的NETT网络协议的实施将利用密尔沃基县紧急医疗服务（EMS）系统和国家认可的成人和儿童创伤中心设在FMLH成人急诊科和毗邻的威斯康星州儿童医院（CHW）儿科急诊科，位于MCW校园获奖模型。Froedtert纪念路德会医院、Froedtert-MCW中风和神经血管中心、威斯康星州儿童医院和密尔沃基县EMS系统将作为密尔沃基枢纽的基础。该地区15家附属护理人员接收社区医院中的8家将作为临床辐条，支持真实的患者评估和招募，并促进研究结果的传播。这些医院是密尔沃基急诊医学研究联盟（MEMRC）的成员，MEMRC是一个经验丰富、久经考验的研究协会，以其支持院内和院外研究的长期基础设施而闻名。密尔沃基中心将利用其庞大的现有研究基础设施，以经济高效的方式实现NETT的目标，提供临床领导、研究支持和当地神经学专业知识;协调IRB活动和人类受试者保护;输入数据、管理合同和监督培训活动。主要研究者和关键人员致力于积极与NETT网络合作，并在社区卫生保健提供者中传播集体活动的成果。密尔沃基中心旨在：1）利用我们现有的基础设施，建立合作关系，以及在EMS和医院环境中进行临床研究的经验（包括紧急情况下知情同意的例外情况）进行选定的NETT临床试验，以提高神经系统紧急情况下临床研究的效率; 2）鼓励多个急诊科和医院参与，以加快神经学研究的患者招募; 3）从MCW和参与医院聘请广泛的研究人员; 4）最大限度地利用我们的成功经验和能力，招募和保留广泛的合格受试者; 5）与其他NETT中心合作，促进研究的转移; 6）与网络成员协调，开发和测试创新的远程医疗方法，让非现场专家参与急诊科神经系统疾病的护理。